A 20-year-old woman with pulmonary embolism and deep vein thrombosis associated with May-Thurner syndrome

May-Thurner syndrome (MTS) is a clinical condition characterized by the compression of the left common iliac vein between the overlying right common iliac artery and the underlying lumbar vertebrae. Although MTS can lead to deep vein thrombosis (DVT) and, in some cases, pulmonary embolism (PE), it r...

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Main Authors: Yusuke Yamazaki, MD, Hidehiko Ikura, MD, Toru Egashira, MD, PhD, Toshimi Kageyama, MD, Masaru Shibata, MD, Kazunori Moritani, MD, PhD, Hideo Mitamura, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S1930043325004418
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author Yusuke Yamazaki, MD
Hidehiko Ikura, MD
Toru Egashira, MD, PhD
Toshimi Kageyama, MD
Masaru Shibata, MD
Kazunori Moritani, MD, PhD
Hideo Mitamura, MD, PhD
author_facet Yusuke Yamazaki, MD
Hidehiko Ikura, MD
Toru Egashira, MD, PhD
Toshimi Kageyama, MD
Masaru Shibata, MD
Kazunori Moritani, MD, PhD
Hideo Mitamura, MD, PhD
author_sort Yusuke Yamazaki, MD
collection DOAJ
description May-Thurner syndrome (MTS) is a clinical condition characterized by the compression of the left common iliac vein between the overlying right common iliac artery and the underlying lumbar vertebrae. Although MTS can lead to deep vein thrombosis (DVT) and, in some cases, pulmonary embolism (PE), it remains underrecognized in clinical practice. We present a case of PE and DVT associated with MTS in a 20-year-old woman with a prolonged history of taking oral contraceptives (OCs). Initial computed tomography angiography (CTA) raised suspicion of MTS, which was further confirmed by Duplex ultrasonography. Anticoagulation therapy, along with discontinuation of OCs, resulted in resolution of thrombi in both the pulmonary and deep venous systems, with no recurrence following cessation of anticoagulation. This case underscores the importance of combining multiple imaging modalities in the evaluation of young women presenting with left-sided DVT, which eventually led to the diagnosis and proper management of MTS.
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issn 1930-0433
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publishDate 2025-09-01
publisher Elsevier
record_format Article
series Radiology Case Reports
spelling doaj-art-fa2c8120c5fd41209fec5da8bfce88bc2025-08-20T03:50:22ZengElsevierRadiology Case Reports1930-04332025-09-012094203420810.1016/j.radcr.2025.05.008A 20-year-old woman with pulmonary embolism and deep vein thrombosis associated with May-Thurner syndromeYusuke Yamazaki, MD0Hidehiko Ikura, MD1Toru Egashira, MD, PhD2Toshimi Kageyama, MD3Masaru Shibata, MD4Kazunori Moritani, MD, PhD5Hideo Mitamura, MD, PhD6Correspondence author.; Department of Cardiology, Tachikawa Hospital, Tokyo, JapanDepartment of Cardiology, Tachikawa Hospital, Tokyo, JapanDepartment of Cardiology, Tachikawa Hospital, Tokyo, JapanDepartment of Cardiology, Tachikawa Hospital, Tokyo, JapanDepartment of Cardiology, Tachikawa Hospital, Tokyo, JapanDepartment of Cardiology, Tachikawa Hospital, Tokyo, JapanDepartment of Cardiology, Tachikawa Hospital, Tokyo, JapanMay-Thurner syndrome (MTS) is a clinical condition characterized by the compression of the left common iliac vein between the overlying right common iliac artery and the underlying lumbar vertebrae. Although MTS can lead to deep vein thrombosis (DVT) and, in some cases, pulmonary embolism (PE), it remains underrecognized in clinical practice. We present a case of PE and DVT associated with MTS in a 20-year-old woman with a prolonged history of taking oral contraceptives (OCs). Initial computed tomography angiography (CTA) raised suspicion of MTS, which was further confirmed by Duplex ultrasonography. Anticoagulation therapy, along with discontinuation of OCs, resulted in resolution of thrombi in both the pulmonary and deep venous systems, with no recurrence following cessation of anticoagulation. This case underscores the importance of combining multiple imaging modalities in the evaluation of young women presenting with left-sided DVT, which eventually led to the diagnosis and proper management of MTS.http://www.sciencedirect.com/science/article/pii/S1930043325004418May-Thurner syndromeIliac vein compression syndromeDeep vein thrombosisPulmonary embolismWomanComputed tomography angiography
spellingShingle Yusuke Yamazaki, MD
Hidehiko Ikura, MD
Toru Egashira, MD, PhD
Toshimi Kageyama, MD
Masaru Shibata, MD
Kazunori Moritani, MD, PhD
Hideo Mitamura, MD, PhD
A 20-year-old woman with pulmonary embolism and deep vein thrombosis associated with May-Thurner syndrome
Radiology Case Reports
May-Thurner syndrome
Iliac vein compression syndrome
Deep vein thrombosis
Pulmonary embolism
Woman
Computed tomography angiography
title A 20-year-old woman with pulmonary embolism and deep vein thrombosis associated with May-Thurner syndrome
title_full A 20-year-old woman with pulmonary embolism and deep vein thrombosis associated with May-Thurner syndrome
title_fullStr A 20-year-old woman with pulmonary embolism and deep vein thrombosis associated with May-Thurner syndrome
title_full_unstemmed A 20-year-old woman with pulmonary embolism and deep vein thrombosis associated with May-Thurner syndrome
title_short A 20-year-old woman with pulmonary embolism and deep vein thrombosis associated with May-Thurner syndrome
title_sort 20 year old woman with pulmonary embolism and deep vein thrombosis associated with may thurner syndrome
topic May-Thurner syndrome
Iliac vein compression syndrome
Deep vein thrombosis
Pulmonary embolism
Woman
Computed tomography angiography
url http://www.sciencedirect.com/science/article/pii/S1930043325004418
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