Rapid food desensitization associated with omalizumab before oral immunotherapy
In this report, we propose an innovative approach to managing patients with food-induced anaphylaxis by performing rapid food desensitization alongside the use of omalizumab as an introductory step to oral immunotherapy. This combined strategy aims to enhance both the safety and effectiveness of the...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | World Allergy Organization Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1939455125000079 |
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| author | Bruna Giavina-Bianchi, MD Pedro Giavina-Bianchi, MD, PhD |
| author_facet | Bruna Giavina-Bianchi, MD Pedro Giavina-Bianchi, MD, PhD |
| author_sort | Bruna Giavina-Bianchi, MD |
| collection | DOAJ |
| description | In this report, we propose an innovative approach to managing patients with food-induced anaphylaxis by performing rapid food desensitization alongside the use of omalizumab as an introductory step to oral immunotherapy. This combined strategy aims to enhance both the safety and effectiveness of the process, which seeks to induce immunological tolerance to food allergens, while reducing the risk of severe allergic reactions during treatment. The use of omalizumab helps prevent anaphylaxis and improves the patient's ability to tolerate the allergen. Rapid desensitization offers significant time and cost savings. As more scientific evidence supports rapid food desensitization, it could become a valuable tool for clinicians managing food-induced anaphylaxis, offering a promising avenue for the treatment of food allergies, especially in complex cases. |
| format | Article |
| id | doaj-art-fa294d172ac6469e806a7f80a981545a |
| institution | Kabale University |
| issn | 1939-4551 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | World Allergy Organization Journal |
| spelling | doaj-art-fa294d172ac6469e806a7f80a981545a2025-01-30T05:13:53ZengElsevierWorld Allergy Organization Journal1939-45512025-02-01182101032Rapid food desensitization associated with omalizumab before oral immunotherapyBruna Giavina-Bianchi, MD0Pedro Giavina-Bianchi, MD, PhD1Clinical Immunology and Allergy Division, University of São Paulo School of Medicine, BrazilCorresponding author. R. Prof. Artur Ramos 178 ap.211, Jd. América, São Paulo, CEP:01454-904 SP, Brazil.; Clinical Immunology and Allergy Division, University of São Paulo School of Medicine, BrazilIn this report, we propose an innovative approach to managing patients with food-induced anaphylaxis by performing rapid food desensitization alongside the use of omalizumab as an introductory step to oral immunotherapy. This combined strategy aims to enhance both the safety and effectiveness of the process, which seeks to induce immunological tolerance to food allergens, while reducing the risk of severe allergic reactions during treatment. The use of omalizumab helps prevent anaphylaxis and improves the patient's ability to tolerate the allergen. Rapid desensitization offers significant time and cost savings. As more scientific evidence supports rapid food desensitization, it could become a valuable tool for clinicians managing food-induced anaphylaxis, offering a promising avenue for the treatment of food allergies, especially in complex cases.http://www.sciencedirect.com/science/article/pii/S1939455125000079Food anaphylaxisRapid desensitizationOral immunotherapyOmalizumabImmunological tolerance |
| spellingShingle | Bruna Giavina-Bianchi, MD Pedro Giavina-Bianchi, MD, PhD Rapid food desensitization associated with omalizumab before oral immunotherapy World Allergy Organization Journal Food anaphylaxis Rapid desensitization Oral immunotherapy Omalizumab Immunological tolerance |
| title | Rapid food desensitization associated with omalizumab before oral immunotherapy |
| title_full | Rapid food desensitization associated with omalizumab before oral immunotherapy |
| title_fullStr | Rapid food desensitization associated with omalizumab before oral immunotherapy |
| title_full_unstemmed | Rapid food desensitization associated with omalizumab before oral immunotherapy |
| title_short | Rapid food desensitization associated with omalizumab before oral immunotherapy |
| title_sort | rapid food desensitization associated with omalizumab before oral immunotherapy |
| topic | Food anaphylaxis Rapid desensitization Oral immunotherapy Omalizumab Immunological tolerance |
| url | http://www.sciencedirect.com/science/article/pii/S1939455125000079 |
| work_keys_str_mv | AT brunagiavinabianchimd rapidfooddesensitizationassociatedwithomalizumabbeforeoralimmunotherapy AT pedrogiavinabianchimdphd rapidfooddesensitizationassociatedwithomalizumabbeforeoralimmunotherapy |