Paternal age in relation to offspring intelligence in the West of Scotland Twenty-07 prospective cohort study.
<h4>Background</h4>The adverse effects of advancing maternal age on offspring's health and development are well understood. Much less is known about the impact of paternal age.<h4>Methods</h4>We explored paternal age-offspring cognition associations in 772 participants f...
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| Language: | English |
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Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0052112&type=printable |
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| author | Elise Whitley Ian J Deary Geoff Der G David Batty Michaela Benzeval |
| author_facet | Elise Whitley Ian J Deary Geoff Der G David Batty Michaela Benzeval |
| author_sort | Elise Whitley |
| collection | DOAJ |
| description | <h4>Background</h4>The adverse effects of advancing maternal age on offspring's health and development are well understood. Much less is known about the impact of paternal age.<h4>Methods</h4>We explored paternal age-offspring cognition associations in 772 participants from the West of Scotland Twenty-07 study. Offspring cognitive ability was assessed using Part 1 of the Alice Heim 4 (AH4) test of General Intelligence and by reaction time (RT).<h4>Results</h4>There was no evidence of a parental age association with offspring RT. However, we observed an inverse U-shaped association between paternal age and offspring AH4 score with the lowest scores observed for the youngest and oldest fathers. Adjustment for parental education and socioeconomic status somewhat attenuated this association. Adjustment for number of, particularly older, siblings further reduced the scores of children of younger fathers and appeared to account for the lower offspring scores in the oldest paternal age group.<h4>Conclusion</h4>We observed a paternal age association with AH4 but not RT, a measure of cognition largely independent of social and educational experiences. Factors such as parental education, socioeconomic status and number of, particularly older, siblings may play an important role in accounting for paternal age-AH4 associations. Future studies should include parental intelligence. |
| format | Article |
| id | doaj-art-fa1dd373c6904a35a759d73ebe2a80b7 |
| institution | DOAJ |
| issn | 1932-6203 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-fa1dd373c6904a35a759d73ebe2a80b72025-08-20T03:09:48ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-01712e5211210.1371/journal.pone.0052112Paternal age in relation to offspring intelligence in the West of Scotland Twenty-07 prospective cohort study.Elise WhitleyIan J DearyGeoff DerG David BattyMichaela Benzeval<h4>Background</h4>The adverse effects of advancing maternal age on offspring's health and development are well understood. Much less is known about the impact of paternal age.<h4>Methods</h4>We explored paternal age-offspring cognition associations in 772 participants from the West of Scotland Twenty-07 study. Offspring cognitive ability was assessed using Part 1 of the Alice Heim 4 (AH4) test of General Intelligence and by reaction time (RT).<h4>Results</h4>There was no evidence of a parental age association with offspring RT. However, we observed an inverse U-shaped association between paternal age and offspring AH4 score with the lowest scores observed for the youngest and oldest fathers. Adjustment for parental education and socioeconomic status somewhat attenuated this association. Adjustment for number of, particularly older, siblings further reduced the scores of children of younger fathers and appeared to account for the lower offspring scores in the oldest paternal age group.<h4>Conclusion</h4>We observed a paternal age association with AH4 but not RT, a measure of cognition largely independent of social and educational experiences. Factors such as parental education, socioeconomic status and number of, particularly older, siblings may play an important role in accounting for paternal age-AH4 associations. Future studies should include parental intelligence.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0052112&type=printable |
| spellingShingle | Elise Whitley Ian J Deary Geoff Der G David Batty Michaela Benzeval Paternal age in relation to offspring intelligence in the West of Scotland Twenty-07 prospective cohort study. PLoS ONE |
| title | Paternal age in relation to offspring intelligence in the West of Scotland Twenty-07 prospective cohort study. |
| title_full | Paternal age in relation to offspring intelligence in the West of Scotland Twenty-07 prospective cohort study. |
| title_fullStr | Paternal age in relation to offspring intelligence in the West of Scotland Twenty-07 prospective cohort study. |
| title_full_unstemmed | Paternal age in relation to offspring intelligence in the West of Scotland Twenty-07 prospective cohort study. |
| title_short | Paternal age in relation to offspring intelligence in the West of Scotland Twenty-07 prospective cohort study. |
| title_sort | paternal age in relation to offspring intelligence in the west of scotland twenty 07 prospective cohort study |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0052112&type=printable |
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