Observational study on Aspergillus infections in critically ill patients with coronavirus disease 2019 at a single medical center using sputum samples
Objective: To explore Aspergillus infection’s risks, treatment, and prognostic factors in critically ill COVID-19 patients. Methodology: Retrospective analysis of 50 critically ill COVID-19 patients' data. Patients were divided into Aspergillus infection group (10 cases) and non-Aspergillus...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Journal of Infection in Developing Countries
2025-05-01
|
| Series: | Journal of Infection in Developing Countries |
| Subjects: | |
| Online Access: | https://jidc.org/index.php/journal/article/view/20072 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Objective: To explore Aspergillus infection’s risks, treatment, and prognostic factors in critically ill COVID-19 patients.
Methodology: Retrospective analysis of 50 critically ill COVID-19 patients' data. Patients were divided into Aspergillus infection group (10 cases) and non-Aspergillus infection group (40 cases) to examine risk factors and compare hospitalization length, expenses, and survival outcomes.
Results: Logistic regression showed a significant correlation between Aspergillus infection and diabetes history, and steroid use duration in COVID-19 patients. Diabetes increased Aspergillus infection risk 9.708 times (not statistically significant). Each extra steroid use day raised infection risk by 25.6%. The Aspergillus infection group had longer hospital stays, and higher costs (p < 0.05) but surprisingly higher survival rate than the non-infection group (p < 0.05).
Conclusions: The main risk factor for Aspergillus infection in critically ill COVID-19 patients is steroid use duration. The infection group had longer hospital stays and higher costs, and Aspergillus infection affected the survival duration of critically ill COVID-19 patients.
|
|---|---|
| ISSN: | 1972-2680 |