Clinical Analysis and Literature Review of 26 Patients with Hematological Malignancies During Pregnancy
Background: The hematological malignancies during pregnancy are rare and lethal. Objective: The aim of this study is to demonstrate the incidence, clinical characteristics, treatment, and outcome of hematological malignancies diagnosed during pregnancy. Methods: This is a retrospective study of wome...
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| Format: | Article |
| Language: | English |
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Mary Ann Liebert
2025-01-01
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| Series: | Women's Health Reports |
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| Online Access: | https://www.liebertpub.com/doi/10.1089/whr.2024.0164 |
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| author | Jie Ma Huimin Zhu Ling Li Hui Ma Bo Zheng |
| author_facet | Jie Ma Huimin Zhu Ling Li Hui Ma Bo Zheng |
| author_sort | Jie Ma |
| collection | DOAJ |
| description | Background: The hematological malignancies during pregnancy are rare and lethal. Objective: The aim of this study is to demonstrate the incidence, clinical characteristics, treatment, and outcome of hematological malignancies diagnosed during pregnancy. Methods: This is a retrospective study of women who were diagnosed with hematological malignancies during pregnancy at an academic hospital between 2001 and 2021. Results: The incidence rate of 26 pregnant women with hematological malignancies in the pregnant patients admitted to the hospital was about 0.07%. Except for one patient who was diagnosed before pregnancy, the incidence rates of the first, second, and third trimesters of pregnancy were 12% (3/25), 48% (12/25), and 40% (10/25), respectively. Eleven out 26 patients (42.3%) finally gave birth to fetuses. In a long-term follow-up, the survival time of patients with leukemia in pregnancy was shorter than lymphoma (p < 0.05). Conclusion: This report provides a comprehensive description of maternal and infant outcomes and insights into the management of hematological malignancies during pregnancy. |
| format | Article |
| id | doaj-art-fa08ff84b7c14dca9abb3d7963a70adf |
| institution | OA Journals |
| issn | 2688-4844 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Mary Ann Liebert |
| record_format | Article |
| series | Women's Health Reports |
| spelling | doaj-art-fa08ff84b7c14dca9abb3d7963a70adf2025-08-20T02:30:55ZengMary Ann LiebertWomen's Health Reports2688-48442025-01-016114715410.1089/whr.2024.0164Clinical Analysis and Literature Review of 26 Patients with Hematological Malignancies During PregnancyJie Ma0Huimin Zhu1Ling Li2Hui Ma3Bo Zheng4Department of Hematology, General Hospital of Ningxia Medical University, Yinchuan City, China.Ningxia rehabilitation medical center, People’s Hospital of Ningxia Hui Autonomous Region, Yinchuan City, China.Department of Hematology, General Hospital of Ningxia Medical University, Yinchuan City, China.Department of Hematology, General Hospital of Ningxia Medical University, Yinchuan City, China.Department of Hematology, General Hospital of Ningxia Medical University, Yinchuan City, China.Background: The hematological malignancies during pregnancy are rare and lethal. Objective: The aim of this study is to demonstrate the incidence, clinical characteristics, treatment, and outcome of hematological malignancies diagnosed during pregnancy. Methods: This is a retrospective study of women who were diagnosed with hematological malignancies during pregnancy at an academic hospital between 2001 and 2021. Results: The incidence rate of 26 pregnant women with hematological malignancies in the pregnant patients admitted to the hospital was about 0.07%. Except for one patient who was diagnosed before pregnancy, the incidence rates of the first, second, and third trimesters of pregnancy were 12% (3/25), 48% (12/25), and 40% (10/25), respectively. Eleven out 26 patients (42.3%) finally gave birth to fetuses. In a long-term follow-up, the survival time of patients with leukemia in pregnancy was shorter than lymphoma (p < 0.05). Conclusion: This report provides a comprehensive description of maternal and infant outcomes and insights into the management of hematological malignancies during pregnancy.https://www.liebertpub.com/doi/10.1089/whr.2024.0164hematological malignanciespregnancypregnancy outcomechemotherapy |
| spellingShingle | Jie Ma Huimin Zhu Ling Li Hui Ma Bo Zheng Clinical Analysis and Literature Review of 26 Patients with Hematological Malignancies During Pregnancy Women's Health Reports hematological malignancies pregnancy pregnancy outcome chemotherapy |
| title | Clinical Analysis and Literature Review of 26 Patients with Hematological Malignancies During Pregnancy |
| title_full | Clinical Analysis and Literature Review of 26 Patients with Hematological Malignancies During Pregnancy |
| title_fullStr | Clinical Analysis and Literature Review of 26 Patients with Hematological Malignancies During Pregnancy |
| title_full_unstemmed | Clinical Analysis and Literature Review of 26 Patients with Hematological Malignancies During Pregnancy |
| title_short | Clinical Analysis and Literature Review of 26 Patients with Hematological Malignancies During Pregnancy |
| title_sort | clinical analysis and literature review of 26 patients with hematological malignancies during pregnancy |
| topic | hematological malignancies pregnancy pregnancy outcome chemotherapy |
| url | https://www.liebertpub.com/doi/10.1089/whr.2024.0164 |
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