Immunization with a heat-killed prm1 deletion strain protects the host from Cryptococcus neoformans infection

Immunization with a heat-killed prm1 deletion strain protects the host from Cryptococcus neoformans infection

Systemic infection with Cryptococcus neoformans, a dangerous and contagious pathogen found throughout the world, frequently results in lethal cryptococcal pneumonia and meningoencephalitis, and no effective treatments and vaccination of cryptococcosis are available. Here, we describe Prm1, a novel r...

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Bibliographic Details
Main Authors: Chao Li, Yang Meng, Hailong Li, Wei Du, Xindi Gao, Chenhao Suo, Yiru Gao, Yue Ni, Tianshu Sun, Sheng Yang, Tian Lan, Meiling Xin, Chen Ding
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
Cryptococcus neoformans
Prm1
cell wall
fungal vaccine
IFN-γ
macrophage polarization
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2244087
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