Context-Seq: CRISPR-Cas9 targeted nanopore sequencing for transmission dynamics of antimicrobial resistance

Context-Seq: CRISPR-Cas9 targeted nanopore sequencing for transmission dynamics of antimicrobial resistance

Abstract Precisely understanding how and to what extent antimicrobial resistance (AMR) is exchanged between animals and humans is needed to inform control strategies. Metagenomic sequencing has low detection for rare targets such as antibiotic resistance genes, while whole genome sequencing of isola...

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Main Authors: Erica R. Fuhrmeister, Sooyeol Kim, Shruteek A. Mairal, Caroline McCormack, Benard Chieng, Jenna M. Swarthout, Abigail Harvey Paulos, Sammy M. Njenga, Amy J. Pickering
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60491-0
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