Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma
Aim. To study the role of vascular endothelial growth factor (VEGF-A) in the fluid of the anterior chamber of the eye (ACE) in the evolvement ofdiabetic retinopathy (DR) and the outcome of cataract surgery. Materials and methods. The study included 120 patients with diabetes mellitus (DM) operated...
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2010-09-01
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| Series: | Сахарный диабет |
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| Online Access: | https://www.dia-endojournals.ru/jour/article/view/5485 |
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| author | Anatoliy Gennad'evich Kuz'min Dmitriy Valentinovich Lipatov Timofey Alexandrovich Chistyakov Olga Mikhailovna Smirnova Margarita Ivanovna Arbuzova Alexander Viktorovich Il'in Marina Vladimirovna Shestakova |
| author_facet | Anatoliy Gennad'evich Kuz'min Dmitriy Valentinovich Lipatov Timofey Alexandrovich Chistyakov Olga Mikhailovna Smirnova Margarita Ivanovna Arbuzova Alexander Viktorovich Il'in Marina Vladimirovna Shestakova |
| author_sort | Anatoliy Gennad'evich Kuz'min |
| collection | DOAJ |
| description | Aim. To study the role of vascular endothelial growth factor (VEGF-A) in the fluid of the anterior chamber of the eye (ACE) in the evolvement ofdiabetic retinopathy (DR) and the outcome of cataract surgery. Materials and methods. The study included 120 patients with diabetes mellitus (DM) operated for the removal of cataract. 16 patients received treatmentfor DR-related neovascular glaucoma (NG). The control group comprised 22 subjects without DM. VEGF-A and glucose levels were measuredin the ACE fluid prior to surgery. Results. Patients with DM were not significantly different in terms of VEGF-A, fasting glucose, and HbA1c levels on the day of surgery excepting DMpatients without DR. VEGF-A and glucose levels in AEG increased in proportion to DR severity. VEGF-A concentration was minimal in the absenceof DR (22.75 pg/ml [10.78; 63.36]) and amounted to 336.6 pg/ml [232.3; 410.74] in patients with DM and DR (P |
| format | Article |
| id | doaj-art-fa064ce190a048269adcb491be8b698c |
| institution | OA Journals |
| issn | 2072-0351 2072-0378 |
| language | English |
| publishDate | 2010-09-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj-art-fa064ce190a048269adcb491be8b698c2025-08-20T02:29:31ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782010-09-01133323610.14341/2072-0351-54855443Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucomaAnatoliy Gennad'evich Kuz'min0Dmitriy Valentinovich Lipatov1Timofey Alexandrovich Chistyakov2Olga Mikhailovna Smirnova3Margarita Ivanovna Arbuzova4Alexander Viktorovich Il'in5Marina Vladimirovna Shestakova6Endocrinological Research Centre, MoscowEndocrinological Research Centre, MoscowEndocrinological Research Centre, MoscowEndocrinological Research Centre, MoscowEndocrinological Research Centre, MoscowEndocrinological Research Centre, MoscowEndocrinological Research Centre, MoscowAim. To study the role of vascular endothelial growth factor (VEGF-A) in the fluid of the anterior chamber of the eye (ACE) in the evolvement ofdiabetic retinopathy (DR) and the outcome of cataract surgery. Materials and methods. The study included 120 patients with diabetes mellitus (DM) operated for the removal of cataract. 16 patients received treatmentfor DR-related neovascular glaucoma (NG). The control group comprised 22 subjects without DM. VEGF-A and glucose levels were measuredin the ACE fluid prior to surgery. Results. Patients with DM were not significantly different in terms of VEGF-A, fasting glucose, and HbA1c levels on the day of surgery excepting DMpatients without DR. VEGF-A and glucose levels in AEG increased in proportion to DR severity. VEGF-A concentration was minimal in the absenceof DR (22.75 pg/ml [10.78; 63.36]) and amounted to 336.6 pg/ml [232.3; 410.74] in patients with DM and DR (Phttps://www.dia-endojournals.ru/jour/article/view/5485vegfvascular endothelial growth factor (vegf-a)diabetic retinopathycataractcataract surgery |
| spellingShingle | Anatoliy Gennad'evich Kuz'min Dmitriy Valentinovich Lipatov Timofey Alexandrovich Chistyakov Olga Mikhailovna Smirnova Margarita Ivanovna Arbuzova Alexander Viktorovich Il'in Marina Vladimirovna Shestakova Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma Сахарный диабет vegf vascular endothelial growth factor (vegf-a) diabetic retinopathy cataract cataract surgery |
| title | Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma |
| title_full | Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma |
| title_fullStr | Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma |
| title_full_unstemmed | Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma |
| title_short | Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma |
| title_sort | vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy cataract andneovascular glaucoma |
| topic | vegf vascular endothelial growth factor (vegf-a) diabetic retinopathy cataract cataract surgery |
| url | https://www.dia-endojournals.ru/jour/article/view/5485 |
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