Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma
Aim. To study the role of vascular endothelial growth factor (VEGF-A) in the fluid of the anterior chamber of the eye (ACE) in the evolvement ofdiabetic retinopathy (DR) and the outcome of cataract surgery. Materials and methods. The study included 120 patients with diabetes mellitus (DM) operated...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Endocrinology Research Centre
2010-09-01
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| Series: | Сахарный диабет |
| Subjects: | |
| Online Access: | https://www.dia-endojournals.ru/jour/article/view/5485 |
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| Summary: | Aim. To study the role of vascular endothelial growth factor (VEGF-A) in the fluid of the anterior chamber of the eye (ACE) in the evolvement ofdiabetic retinopathy (DR) and the outcome of cataract surgery. Materials and methods. The study included 120 patients with diabetes mellitus (DM) operated for the removal of cataract. 16 patients received treatmentfor DR-related neovascular glaucoma (NG). The control group comprised 22 subjects without DM. VEGF-A and glucose levels were measuredin the ACE fluid prior to surgery. Results. Patients with DM were not significantly different in terms of VEGF-A, fasting glucose, and HbA1c levels on the day of surgery excepting DMpatients without DR. VEGF-A and glucose levels in AEG increased in proportion to DR severity. VEGF-A concentration was minimal in the absenceof DR (22.75 pg/ml [10.78; 63.36]) and amounted to 336.6 pg/ml [232.3; 410.74] in patients with DM and DR (P |
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| ISSN: | 2072-0351 2072-0378 |