Acute Lymphocytic Leukemia with Skin Infiltration. Case Report and Literature Review

Cutaneous leukemia is a very rare pathology and can occur in different types of leukemia associated or not with genetic syndromes. It is a very uncommon form of initial presentation of malignancy. Due to its non-specific skin lesions and the similarity with various skin pathologies, it represents a...

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Main Author: Adrian Isacc Nieto Jiménez
Format: Article
Language:Spanish
Published: Universidad de las Ciencias Médicas de Cienfuegos 2022-08-01
Series:Revista Finlay
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Online Access:https://revfinlay.sld.cu/index.php/finlay/article/view/1123
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author Adrian Isacc Nieto Jiménez
author_facet Adrian Isacc Nieto Jiménez
author_sort Adrian Isacc Nieto Jiménez
collection DOAJ
description Cutaneous leukemia is a very rare pathology and can occur in different types of leukemia associated or not with genetic syndromes. It is a very uncommon form of initial presentation of malignancy. Due to its non-specific skin lesions and the similarity with various skin pathologies, it represents a great diagnostic challenge for the pediatric dermatologist. We present the case of a 5-year-old boy with a history of acute lymphocytic leukemia with scaly papular lesions of a lichenoid appearance disseminated in the cutaneous integument. A skin biopsy was performed on suspicion of skin infiltration or leukemia cutis. The case was discussed to reach diagnostic confirmation of cutaneous leukemia. Treatment was started in the Hematology Service. This hematological disease occasionally manifests itself on the skin and when it does, it is necessary to recognize it to complete its diagnosis and treatment and save the life of the affected patient, as in this case. The interest of this presentation lies in the fact that the appearance of skin lesions, even if they are non-specific, in a patient with leukemia, should alert the treating medical team for their rapid study and thus guide therapeutic behavior and due to their low incidence of presentation.
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spelling doaj-art-fa0302a8089e41479b97c7931fe6dc4f2025-01-30T21:22:01ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342022-08-01123357363582Acute Lymphocytic Leukemia with Skin Infiltration. Case Report and Literature ReviewAdrian Isacc Nieto Jiménez0Hospital Pediátrico Universitario José Luis Miranda. Villa Clara.Cutaneous leukemia is a very rare pathology and can occur in different types of leukemia associated or not with genetic syndromes. It is a very uncommon form of initial presentation of malignancy. Due to its non-specific skin lesions and the similarity with various skin pathologies, it represents a great diagnostic challenge for the pediatric dermatologist. We present the case of a 5-year-old boy with a history of acute lymphocytic leukemia with scaly papular lesions of a lichenoid appearance disseminated in the cutaneous integument. A skin biopsy was performed on suspicion of skin infiltration or leukemia cutis. The case was discussed to reach diagnostic confirmation of cutaneous leukemia. Treatment was started in the Hematology Service. This hematological disease occasionally manifests itself on the skin and when it does, it is necessary to recognize it to complete its diagnosis and treatment and save the life of the affected patient, as in this case. The interest of this presentation lies in the fact that the appearance of skin lesions, even if they are non-specific, in a patient with leukemia, should alert the treating medical team for their rapid study and thus guide therapeutic behavior and due to their low incidence of presentation.https://revfinlay.sld.cu/index.php/finlay/article/view/1123leucemia linfocítica agudalesiones cutáneasreporte de casos
spellingShingle Adrian Isacc Nieto Jiménez
Acute Lymphocytic Leukemia with Skin Infiltration. Case Report and Literature Review
Revista Finlay
leucemia linfocítica aguda
lesiones cutáneas
reporte de casos
title Acute Lymphocytic Leukemia with Skin Infiltration. Case Report and Literature Review
title_full Acute Lymphocytic Leukemia with Skin Infiltration. Case Report and Literature Review
title_fullStr Acute Lymphocytic Leukemia with Skin Infiltration. Case Report and Literature Review
title_full_unstemmed Acute Lymphocytic Leukemia with Skin Infiltration. Case Report and Literature Review
title_short Acute Lymphocytic Leukemia with Skin Infiltration. Case Report and Literature Review
title_sort acute lymphocytic leukemia with skin infiltration case report and literature review
topic leucemia linfocítica aguda
lesiones cutáneas
reporte de casos
url https://revfinlay.sld.cu/index.php/finlay/article/view/1123
work_keys_str_mv AT adrianisaccnietojimenez acutelymphocyticleukemiawithskininfiltrationcasereportandliteraturereview