A review of recent research on the antimicrobial activities of thiosemicarbazone-based compounds

Thiosemicarbazones can be synthesized by condensation of thiosemicarbazides with ketones or aldehydes and play a role as precursors in the synthesis of many compounds such as thiazoles. They can exhibit many biological activities such as anti-inflammatory, antitumor, and antimicrobial properties. Th...

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Main Author: Gürsel Korkmaz
Format: Article
Language:English
Published: Tokat Gaziosmanpasa University 2024-04-01
Series:Journal of New Results in Science
Subjects:
Online Access:https://dergipark.org.tr/en/download/article-file/3846286
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author Gürsel Korkmaz
author_facet Gürsel Korkmaz
author_sort Gürsel Korkmaz
collection DOAJ
description Thiosemicarbazones can be synthesized by condensation of thiosemicarbazides with ketones or aldehydes and play a role as precursors in the synthesis of many compounds such as thiazoles. They can exhibit many biological activities such as anti-inflammatory, antitumor, and antimicrobial properties. The discovery of antibiotics was an important milestone in the treatment of bacterial infections. However, antimicrobial resistance developed by microorganisms has created the need to discover new antimicrobial agents. Thiosemicarbazones and thiosemicarbazone-based compounds show significant antimicrobial potential. This review investigates the antimicrobial activity results of 244 Thiosemicarbazones and Thiosemicarbazone-based compounds over the last five years. We summarized some articles on thiosemicarbazones and their hybrids showing only antibacterial and antifungal activity in Web of Science (WOS) between 2019 and 2024.
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language English
publishDate 2024-04-01
publisher Tokat Gaziosmanpasa University
record_format Article
series Journal of New Results in Science
spelling doaj-art-fa00ba57c50b4cd1a477a0f2b61453b72025-08-20T03:44:20ZengTokat Gaziosmanpasa UniversityJournal of New Results in Science1304-79812024-04-01131618310.54187/jnrs.1464723142A review of recent research on the antimicrobial activities of thiosemicarbazone-based compoundsGürsel Korkmaz0https://orcid.org/0000-0003-4855-2907SİVAS CUMHURİYET ÜNİVERSİTESİ, SİVAS TEKNİK BİLİMLER MESLEK YÜKSEKOKULUThiosemicarbazones can be synthesized by condensation of thiosemicarbazides with ketones or aldehydes and play a role as precursors in the synthesis of many compounds such as thiazoles. They can exhibit many biological activities such as anti-inflammatory, antitumor, and antimicrobial properties. The discovery of antibiotics was an important milestone in the treatment of bacterial infections. However, antimicrobial resistance developed by microorganisms has created the need to discover new antimicrobial agents. Thiosemicarbazones and thiosemicarbazone-based compounds show significant antimicrobial potential. This review investigates the antimicrobial activity results of 244 Thiosemicarbazones and Thiosemicarbazone-based compounds over the last five years. We summarized some articles on thiosemicarbazones and their hybrids showing only antibacterial and antifungal activity in Web of Science (WOS) between 2019 and 2024.https://dergipark.org.tr/en/download/article-file/3846286thiosemicarbazoneantimicrobialantibacterialantifungalbiological activity
spellingShingle Gürsel Korkmaz
A review of recent research on the antimicrobial activities of thiosemicarbazone-based compounds
Journal of New Results in Science
thiosemicarbazone
antimicrobial
antibacterial
antifungal
biological activity
title A review of recent research on the antimicrobial activities of thiosemicarbazone-based compounds
title_full A review of recent research on the antimicrobial activities of thiosemicarbazone-based compounds
title_fullStr A review of recent research on the antimicrobial activities of thiosemicarbazone-based compounds
title_full_unstemmed A review of recent research on the antimicrobial activities of thiosemicarbazone-based compounds
title_short A review of recent research on the antimicrobial activities of thiosemicarbazone-based compounds
title_sort review of recent research on the antimicrobial activities of thiosemicarbazone based compounds
topic thiosemicarbazone
antimicrobial
antibacterial
antifungal
biological activity
url https://dergipark.org.tr/en/download/article-file/3846286
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