Targeted Therapy for Rheumatoid Arthritis in the New Era

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. The clinical manifestation of RA involves various organs and systems both inside and outside the joints, and often exhibits strong clinical heterogeneity with unclear pathogenesis. Ineffective drug treatment for severe arthritis can...

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Main Authors: WANG Jun, MENG Juan
Format: Article
Language:zho
Published: Editorial Office of Medical Journal of Peking Union Medical College Hospital 2025-01-01
Series:Xiehe Yixue Zazhi
Subjects:
Online Access:https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0842
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author WANG Jun
MENG Juan
author_facet WANG Jun
MENG Juan
author_sort WANG Jun
collection DOAJ
description Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. The clinical manifestation of RA involves various organs and systems both inside and outside the joints, and often exhibits strong clinical heterogeneity with unclear pathogenesis. Ineffective drug treatment for severe arthritis can result in physical disability and severely decreased quality of life. In recent years, targeted therapy for RA has become a hot research topic and has made new breakthroughs. Targeted treatments for RA mainly include two categories: biologic and targeted synthetic disease-modifying antirheumatic drugs. This article aims to elaborate on the current research status and progress of these drugs, with the hope of providing insights for clinicians to better guide personalized treatment for RA patients.
format Article
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institution Kabale University
issn 1674-9081
language zho
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publisher Editorial Office of Medical Journal of Peking Union Medical College Hospital
record_format Article
series Xiehe Yixue Zazhi
spelling doaj-art-f9fc935068e14e889a269f74ea761d692025-02-08T07:47:34ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812025-01-01161192710.12290/xhyxzz.2024-0842Targeted Therapy for Rheumatoid Arthritis in the New EraWANG Jun0MENG Juan1Rheumatology and Immunology Department, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, ChinaRheumatology and Immunology Department, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, ChinaRheumatoid arthritis (RA) is a chronic systemic autoimmune disease. The clinical manifestation of RA involves various organs and systems both inside and outside the joints, and often exhibits strong clinical heterogeneity with unclear pathogenesis. Ineffective drug treatment for severe arthritis can result in physical disability and severely decreased quality of life. In recent years, targeted therapy for RA has become a hot research topic and has made new breakthroughs. Targeted treatments for RA mainly include two categories: biologic and targeted synthetic disease-modifying antirheumatic drugs. This article aims to elaborate on the current research status and progress of these drugs, with the hope of providing insights for clinicians to better guide personalized treatment for RA patients.https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0842rheumatoid arthritistargeted therapybiologic disease-modifying antirheumatic drugstargeted synthetic disease-modifying antirheumatic drugs
spellingShingle WANG Jun
MENG Juan
Targeted Therapy for Rheumatoid Arthritis in the New Era
Xiehe Yixue Zazhi
rheumatoid arthritis
targeted therapy
biologic disease-modifying antirheumatic drugs
targeted synthetic disease-modifying antirheumatic drugs
title Targeted Therapy for Rheumatoid Arthritis in the New Era
title_full Targeted Therapy for Rheumatoid Arthritis in the New Era
title_fullStr Targeted Therapy for Rheumatoid Arthritis in the New Era
title_full_unstemmed Targeted Therapy for Rheumatoid Arthritis in the New Era
title_short Targeted Therapy for Rheumatoid Arthritis in the New Era
title_sort targeted therapy for rheumatoid arthritis in the new era
topic rheumatoid arthritis
targeted therapy
biologic disease-modifying antirheumatic drugs
targeted synthetic disease-modifying antirheumatic drugs
url https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0842
work_keys_str_mv AT wangjun targetedtherapyforrheumatoidarthritisinthenewera
AT mengjuan targetedtherapyforrheumatoidarthritisinthenewera