Twelve‐month change in quantitative MRI calf muscle fat fraction in CMT1A predicts clinical change over 4 years
Abstract Objective We measured clinical and quantitative MRI outcome measures in CMT1A to assess long‐term responsiveness, establish longitudinal validity and assess MRI as a bridging biomarker. Methods Twenty patients with CMT1A and 20 matched controls underwent MRI, myometry and clinical assessmen...
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| Main Authors: | Matthew R. B. Evans, Hamza A. Salhab, Christopher D. J. Sinclair, Sachit Shah, Michael G. Hanna, Tarek A. Yousry, John S. Thornton, Jasper M. Morrow, Mary M. Reilly |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-04-01
|
| Series: | Annals of Clinical and Translational Neurology |
| Online Access: | https://doi.org/10.1002/acn3.52314 |
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