Butyrate improves abnormal sleep architecture in a Parkinson’s disease mouse model via BDNF/TrkB signaling
Abstract Sleep disturbances are among the most prevalent non-motor symptoms of Parkinson’s disease (PD), yet their underlying mechanisms remain inadequately understood. Emerging evidence has emphasized a strong association between gut health and sleep stability, with notable early alterations in mic...
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| Main Authors: | Wen-Xiang Duan, Wei-Ye Xie, Chen Ying, Wang Fen, Xiao-Yu Cheng, Cheng-Jie Mao, Jun-Yi Liu, Chun-Feng Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
|
| Series: | npj Parkinson's Disease |
| Online Access: | https://doi.org/10.1038/s41531-025-01029-5 |
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