Butyrate improves abnormal sleep architecture in a Parkinson’s disease mouse model via BDNF/TrkB signaling

Abstract Sleep disturbances are among the most prevalent non-motor symptoms of Parkinson’s disease (PD), yet their underlying mechanisms remain inadequately understood. Emerging evidence has emphasized a strong association between gut health and sleep stability, with notable early alterations in mic...

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Bibliographic Details
Main Authors: Wen-Xiang Duan, Wei-Ye Xie, Chen Ying, Wang Fen, Xiao-Yu Cheng, Cheng-Jie Mao, Jun-Yi Liu, Chun-Feng Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-01029-5
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