Synthesis and Characterization of New Diketone Analogues of Podophyllotoxin
The new compounds 6,6a-dihydro-2,3-dimethoxy-9-nitro–11bH benzo [C]-fluoren 5,7-dione, 6,6a-dihydro-2,3-dimethoxy-9-chloro–11bH benzo[C]-fluoren-5,7-dione and 6,6a-dihydro-2,3-dimethoxy-9-fluoro–11bH benzo[C]-fluoren-5,7- dione were synthesized in high yields. They are analogues of naturally occurri...
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| Format: | Article |
| Language: | English |
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Wiley
2008-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2008/314724 |
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| _version_ | 1832567347761643520 |
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| author | K. H. Hemakumar A. D. Sathisha Y. B. Basavaraju |
| author_facet | K. H. Hemakumar A. D. Sathisha Y. B. Basavaraju |
| author_sort | K. H. Hemakumar |
| collection | DOAJ |
| description | The new compounds 6,6a-dihydro-2,3-dimethoxy-9-nitro–11bH benzo [C]-fluoren 5,7-dione, 6,6a-dihydro-2,3-dimethoxy-9-chloro–11bH benzo[C]-fluoren-5,7-dione and 6,6a-dihydro-2,3-dimethoxy-9-fluoro–11bH benzo[C]-fluoren-5,7- dione were synthesized in high yields. They are analogues of naturally occurring lignan podophyllotoxin which exhibits anticancer activity. They are very essential to study anticancer activity. |
| format | Article |
| id | doaj-art-f9be9ce380c64a609fb9b273abeeea14 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2008-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-f9be9ce380c64a609fb9b273abeeea142025-02-03T01:01:44ZengWileyE-Journal of Chemistry0973-49452090-98102008-01-015111411910.1155/2008/314724Synthesis and Characterization of New Diketone Analogues of PodophyllotoxinK. H. Hemakumar0A. D. Sathisha1Y. B. Basavaraju2Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore-570 006, Karnataka, IndiaDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore-570 006, Karnataka, IndiaDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore-570 006, Karnataka, IndiaThe new compounds 6,6a-dihydro-2,3-dimethoxy-9-nitro–11bH benzo [C]-fluoren 5,7-dione, 6,6a-dihydro-2,3-dimethoxy-9-chloro–11bH benzo[C]-fluoren-5,7-dione and 6,6a-dihydro-2,3-dimethoxy-9-fluoro–11bH benzo[C]-fluoren-5,7- dione were synthesized in high yields. They are analogues of naturally occurring lignan podophyllotoxin which exhibits anticancer activity. They are very essential to study anticancer activity.http://dx.doi.org/10.1155/2008/314724 |
| spellingShingle | K. H. Hemakumar A. D. Sathisha Y. B. Basavaraju Synthesis and Characterization of New Diketone Analogues of Podophyllotoxin E-Journal of Chemistry |
| title | Synthesis and Characterization of New Diketone Analogues of Podophyllotoxin |
| title_full | Synthesis and Characterization of New Diketone Analogues of Podophyllotoxin |
| title_fullStr | Synthesis and Characterization of New Diketone Analogues of Podophyllotoxin |
| title_full_unstemmed | Synthesis and Characterization of New Diketone Analogues of Podophyllotoxin |
| title_short | Synthesis and Characterization of New Diketone Analogues of Podophyllotoxin |
| title_sort | synthesis and characterization of new diketone analogues of podophyllotoxin |
| url | http://dx.doi.org/10.1155/2008/314724 |
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