A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation
Several studies report on traumatic history in Obsessive Compulsive Disorder (OCD) and comorbidity between Posttraumatic Stress Disorder (PTSD) and OCD. First-line pharmacological treatments for both OCD and PTSD are primarily based on antidepressants, including Selective Serotonin Reuptake Inhibito...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2020/2616492 |
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| author | Rodolfo Rossi Cinzia Niolu Alberto Siracusano Alessandro Rossi Giorgio Di Lorenzo |
| author_facet | Rodolfo Rossi Cinzia Niolu Alberto Siracusano Alessandro Rossi Giorgio Di Lorenzo |
| author_sort | Rodolfo Rossi |
| collection | DOAJ |
| description | Several studies report on traumatic history in Obsessive Compulsive Disorder (OCD) and comorbidity between Posttraumatic Stress Disorder (PTSD) and OCD. First-line pharmacological treatments for both OCD and PTSD are primarily based on antidepressants, including Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin-Noradrenaline Reuptake Inhibitors (SNRI) such as Venlafaxine for PTSD. Second-Generation Antipsychotic (SGA) augmentation has shown good outcomes for nonresponsive OCD cases. However, evidence on the use of SGA in PTSD is more limited. In the present paper, we report on comorbid OCD-PTSD successfully treated with aripiprazole augmentation of sertraline. Shared psychopathological and pharmacological aspects of the disorders are discussed. |
| format | Article |
| id | doaj-art-f9b5fd8dd36f4a3099e784cf7ae246f0 |
| institution | Kabale University |
| issn | 2090-682X 2090-6838 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj-art-f9b5fd8dd36f4a3099e784cf7ae246f02025-02-03T01:04:59ZengWileyCase Reports in Psychiatry2090-682X2090-68382020-01-01202010.1155/2020/26164922616492A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole AugmentationRodolfo Rossi0Cinzia Niolu1Alberto Siracusano2Alessandro Rossi3Giorgio Di Lorenzo4Chair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Rome, ItalyChair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Rome, ItalyChair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Rome, ItalyDepartment of Applied Clinical Sciences and Biotechnologies, University of L’Aquila, Via Vetoio, 67100 L’Aquila, ItalyChair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Rome, ItalySeveral studies report on traumatic history in Obsessive Compulsive Disorder (OCD) and comorbidity between Posttraumatic Stress Disorder (PTSD) and OCD. First-line pharmacological treatments for both OCD and PTSD are primarily based on antidepressants, including Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin-Noradrenaline Reuptake Inhibitors (SNRI) such as Venlafaxine for PTSD. Second-Generation Antipsychotic (SGA) augmentation has shown good outcomes for nonresponsive OCD cases. However, evidence on the use of SGA in PTSD is more limited. In the present paper, we report on comorbid OCD-PTSD successfully treated with aripiprazole augmentation of sertraline. Shared psychopathological and pharmacological aspects of the disorders are discussed.http://dx.doi.org/10.1155/2020/2616492 |
| spellingShingle | Rodolfo Rossi Cinzia Niolu Alberto Siracusano Alessandro Rossi Giorgio Di Lorenzo A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation Case Reports in Psychiatry |
| title | A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation |
| title_full | A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation |
| title_fullStr | A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation |
| title_full_unstemmed | A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation |
| title_short | A Case of Comorbid PTSD and Posttraumatic OCD Treated with Sertraline-Aripiprazole Augmentation |
| title_sort | case of comorbid ptsd and posttraumatic ocd treated with sertraline aripiprazole augmentation |
| url | http://dx.doi.org/10.1155/2020/2616492 |
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