Regulation of YAP and Wnt signaling by the endosomal protein MAMDC4.

Regulation of YAP and Wnt signaling by the endosomal protein MAMDC4.

Maintenance of the intestinal epithelium requires constant self-renewal and regeneration. Tight regulation of proliferation and differentiation of intestinal stem cells within the crypt region is critical to maintaining homeostasis. The transcriptional co-factors β-catenin and YAP are required for p...

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Main Authors: Christopher M Cox, Meng-Han Wu, Marco Padilla-Rodriguez, Isabella Blum, Samina Momtaz, Stefanie A T Mitchell, Jean M Wilson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0296003&type=printable
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