Investigation of fractional compartmental models in pharmacokinetics with application to amiodarone drug diffusion

Investigation of fractional compartmental models in pharmacokinetics with application to amiodarone drug diffusion

This study offers and explores fractional models derived from a classical Pharmacokinetics (PK) compartmental system. The fractional models are essentially enlarged versions of the classical model, and their distinguishing characteristics are further examined comprehensively. Through numerical simul...

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Bibliographic Details
Main Authors: Reindorf Nartey Borkor, Adu Sakyi, Nicholas Kwasi-Do Ohene Opoku, Rhydal Esi Eghan, John Amoah-Mensah, Ali Abubakar, Kwame Owusu Edusei, Peter Amoako-Yirenkyi
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Scientific African
Subjects:
Fractional calculus
Pharmacokinetics
Grunwald–Letnikov derivative
Compartmental models
Online Access:http://www.sciencedirect.com/science/article/pii/S246822762500170X
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