The study for asthma in older adults: a combined analysis of the effects of occupational asthmagens, high body-mass index and smoking
BackgroundAsthma remains a significant public health challenge globally, particularly among older adults who face diagnostic complexity, atypical symptom profiles, and frequent comorbidities. Despite global advances in asthma control, little attention has been paid to the evolving composition and ge...
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1625623/full |
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| author | Jia-Qi Wang Jia-Qi Wang Yuan-Yu Liang Yuan-Yu Liang Zhong-Xue Zhao Zhong-Xue Zhao Wei Xie Wan-Ning Sun Wan-Ning Sun Ji-Yu Zou Ji-Yu Zou Xiao-Dong Lv Xiao-Dong Lv Youfu He Li-Jian Pang Li-Jian Pang |
| author_facet | Jia-Qi Wang Jia-Qi Wang Yuan-Yu Liang Yuan-Yu Liang Zhong-Xue Zhao Zhong-Xue Zhao Wei Xie Wan-Ning Sun Wan-Ning Sun Ji-Yu Zou Ji-Yu Zou Xiao-Dong Lv Xiao-Dong Lv Youfu He Li-Jian Pang Li-Jian Pang |
| author_sort | Jia-Qi Wang |
| collection | DOAJ |
| description | BackgroundAsthma remains a significant public health challenge globally, particularly among older adults who face diagnostic complexity, atypical symptom profiles, and frequent comorbidities. Despite global advances in asthma control, little attention has been paid to the evolving composition and geographic disparity of modifiable risk factors in this age group.MethodsWe utilized data from the Global Burden of Disease Study 2021 to evaluate the long-term trends (1990–2021) in asthma burden attributable to high body-mass index (BMI), smoking, and occupational asthmagens among adults aged 60 years and older. Key metrics included age-standardized mortality rates (ASMR), age-standardized DALY rates (ASDR), and estimated annual percentage change (EAPC). Stratified analyses were conducted across Socio-demographic Index (SDI) quintiles, gender, and detailed 5-year age subgroups (60–64 to ≥95 years) to assess disparities across socioeconomic development, gender, and aging patterns, with additional stratification by geographic region.ResultsFrom 1990 to 2021, asthma burden attributable to smoking and occupational asthmagens among older adults declined globally, while high BMI-related burden increased in several middle and low SDI regions. In terms of attribution proportion, the proportion of asthma deaths attributable to high BMI increased from 10.89 to 14.4%, with this upward trend being particularly pronounced in high SDI regions. Occupational asthmagens-related burden showed limited decline and remained elevated in low SDI regions. Gender-stratified analysis showed that the risk burden of smoking was higher in older men in Asia, whereas the high BMI-related burden was higher in women in more developed regions.ConclusionThis study demonstrates a structural shift in the composition of asthma risk factors among older adults, with high BMI emerging as a dominant contributor amid declining traditional behavioral risks such as smoking. There are significant differences among regions, age groups and genders. Targeted, region-specific strategies are essential to address these evolving risks and reduce inequities in asthma burden among aging populations. |
| format | Article |
| id | doaj-art-f97d38ea3384489d864348552d4ea838 |
| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Public Health |
| spelling | doaj-art-f97d38ea3384489d864348552d4ea8382025-08-20T03:31:20ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-07-011310.3389/fpubh.2025.16256231625623The study for asthma in older adults: a combined analysis of the effects of occupational asthmagens, high body-mass index and smokingJia-Qi Wang0Jia-Qi Wang1Yuan-Yu Liang2Yuan-Yu Liang3Zhong-Xue Zhao4Zhong-Xue Zhao5Wei Xie6Wan-Ning Sun7Wan-Ning Sun8Ji-Yu Zou9Ji-Yu Zou10Xiao-Dong Lv11Xiao-Dong Lv12Youfu He13Li-Jian Pang14Li-Jian Pang15The First Clinical College, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaDepartment of Pulmonology II, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaThe First Clinical College, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaDepartment of Pulmonology II, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaThe First Clinical College, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaDepartment of Pulmonology II, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaTianjin Key Laboratory of Exercise Physiology and Sports Medicine, Institute of Sport, Exercise and Health, Tianjin University of Sport, Tianjin, ChinaThe First Clinical College, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaDepartment of Pulmonology II, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaThe First Clinical College, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaDepartment of Pulmonology II, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaThe First Clinical College, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaDepartment of Pulmonology II, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaDepartment of Cardiology, Guizhou Provincial People's Hospital, Guiyang, ChinaThe First Clinical College, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaDepartment of Pulmonology II, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, ChinaBackgroundAsthma remains a significant public health challenge globally, particularly among older adults who face diagnostic complexity, atypical symptom profiles, and frequent comorbidities. Despite global advances in asthma control, little attention has been paid to the evolving composition and geographic disparity of modifiable risk factors in this age group.MethodsWe utilized data from the Global Burden of Disease Study 2021 to evaluate the long-term trends (1990–2021) in asthma burden attributable to high body-mass index (BMI), smoking, and occupational asthmagens among adults aged 60 years and older. Key metrics included age-standardized mortality rates (ASMR), age-standardized DALY rates (ASDR), and estimated annual percentage change (EAPC). Stratified analyses were conducted across Socio-demographic Index (SDI) quintiles, gender, and detailed 5-year age subgroups (60–64 to ≥95 years) to assess disparities across socioeconomic development, gender, and aging patterns, with additional stratification by geographic region.ResultsFrom 1990 to 2021, asthma burden attributable to smoking and occupational asthmagens among older adults declined globally, while high BMI-related burden increased in several middle and low SDI regions. In terms of attribution proportion, the proportion of asthma deaths attributable to high BMI increased from 10.89 to 14.4%, with this upward trend being particularly pronounced in high SDI regions. Occupational asthmagens-related burden showed limited decline and remained elevated in low SDI regions. Gender-stratified analysis showed that the risk burden of smoking was higher in older men in Asia, whereas the high BMI-related burden was higher in women in more developed regions.ConclusionThis study demonstrates a structural shift in the composition of asthma risk factors among older adults, with high BMI emerging as a dominant contributor amid declining traditional behavioral risks such as smoking. There are significant differences among regions, age groups and genders. Targeted, region-specific strategies are essential to address these evolving risks and reduce inequities in asthma burden among aging populations.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1625623/fullasthma burdenhigh body-mass indexsmokingoccupational asthmagensolder adults |
| spellingShingle | Jia-Qi Wang Jia-Qi Wang Yuan-Yu Liang Yuan-Yu Liang Zhong-Xue Zhao Zhong-Xue Zhao Wei Xie Wan-Ning Sun Wan-Ning Sun Ji-Yu Zou Ji-Yu Zou Xiao-Dong Lv Xiao-Dong Lv Youfu He Li-Jian Pang Li-Jian Pang The study for asthma in older adults: a combined analysis of the effects of occupational asthmagens, high body-mass index and smoking Frontiers in Public Health asthma burden high body-mass index smoking occupational asthmagens older adults |
| title | The study for asthma in older adults: a combined analysis of the effects of occupational asthmagens, high body-mass index and smoking |
| title_full | The study for asthma in older adults: a combined analysis of the effects of occupational asthmagens, high body-mass index and smoking |
| title_fullStr | The study for asthma in older adults: a combined analysis of the effects of occupational asthmagens, high body-mass index and smoking |
| title_full_unstemmed | The study for asthma in older adults: a combined analysis of the effects of occupational asthmagens, high body-mass index and smoking |
| title_short | The study for asthma in older adults: a combined analysis of the effects of occupational asthmagens, high body-mass index and smoking |
| title_sort | study for asthma in older adults a combined analysis of the effects of occupational asthmagens high body mass index and smoking |
| topic | asthma burden high body-mass index smoking occupational asthmagens older adults |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1625623/full |
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