Bilateral Diffuse Fluorodeoxyglucose Uptake in Thyroid Gland Diagnosed by Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography

Our patient is a female who was first diagnosed with breast cancer at the age of 23. A follow-up fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) at age 44 revealed diffuse high FDG uptake in an enlarged thyroid gland. Fine-needle aspiration (FNA) of the thyroid mass...

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Main Authors: Aung Win, Carina Aparici
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2014-04-01
Series:World Journal of Nuclear Medicine
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.139147
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author Aung Win
Carina Aparici
author_facet Aung Win
Carina Aparici
author_sort Aung Win
collection DOAJ
description Our patient is a female who was first diagnosed with breast cancer at the age of 23. A follow-up fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) at age 44 revealed diffuse high FDG uptake in an enlarged thyroid gland. Fine-needle aspiration (FNA) of the thyroid mass revealed estrogen receptor/progesterone receptor negative, human epidermal growth factor receptor 2+ breast cancer. To the best of our knowledge, this is the first case to report breast cancer metastasis to the thyroid in a diffuse pattern on FDG-PET/CT. Bilateral diffuse uptake of FDG in thyroid is the most commonly associated with benign conditions. However, FNA biopsies need to be done to rule out metastatic disease in thyroid lesions with diffuse high FDG uptake, especially for patients with history of cancer.
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series World Journal of Nuclear Medicine
spelling doaj-art-f96d2e88ad53445b8f33628e87f2024f2025-08-20T03:48:36ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122014-04-01130213814110.4103/1450-1147.139147Bilateral Diffuse Fluorodeoxyglucose Uptake in Thyroid Gland Diagnosed by Fluorodeoxyglucose-Positron Emission Tomography/Computed TomographyAung Win0Carina Aparici1Department of Radiology, Nuclear Medicine Section, San Francisco Veteran Affairs Medical Center, San Francisco, CA, USADepartment of Radiology, UCSF, San Francisco, CA, USAOur patient is a female who was first diagnosed with breast cancer at the age of 23. A follow-up fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) at age 44 revealed diffuse high FDG uptake in an enlarged thyroid gland. Fine-needle aspiration (FNA) of the thyroid mass revealed estrogen receptor/progesterone receptor negative, human epidermal growth factor receptor 2+ breast cancer. To the best of our knowledge, this is the first case to report breast cancer metastasis to the thyroid in a diffuse pattern on FDG-PET/CT. Bilateral diffuse uptake of FDG in thyroid is the most commonly associated with benign conditions. However, FNA biopsies need to be done to rule out metastatic disease in thyroid lesions with diffuse high FDG uptake, especially for patients with history of cancer.http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.139147breast cancerdiffusefluorodeoxyglucose-positron emission tomography/computed tomographymetastasisthyroid
spellingShingle Aung Win
Carina Aparici
Bilateral Diffuse Fluorodeoxyglucose Uptake in Thyroid Gland Diagnosed by Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography
World Journal of Nuclear Medicine
breast cancer
diffuse
fluorodeoxyglucose-positron emission tomography/computed tomography
metastasis
thyroid
title Bilateral Diffuse Fluorodeoxyglucose Uptake in Thyroid Gland Diagnosed by Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography
title_full Bilateral Diffuse Fluorodeoxyglucose Uptake in Thyroid Gland Diagnosed by Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography
title_fullStr Bilateral Diffuse Fluorodeoxyglucose Uptake in Thyroid Gland Diagnosed by Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography
title_full_unstemmed Bilateral Diffuse Fluorodeoxyglucose Uptake in Thyroid Gland Diagnosed by Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography
title_short Bilateral Diffuse Fluorodeoxyglucose Uptake in Thyroid Gland Diagnosed by Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography
title_sort bilateral diffuse fluorodeoxyglucose uptake in thyroid gland diagnosed by fluorodeoxyglucose positron emission tomography computed tomography
topic breast cancer
diffuse
fluorodeoxyglucose-positron emission tomography/computed tomography
metastasis
thyroid
url http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.139147
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