The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking

The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking

Epithelial-mesenchymal transition (EMT) plays important roles in tumour progression and is orchestrated by dynamic changes in gene expression. While it is well established that post-transcriptional regulation plays a significant role in EMT, the extent of alternative polyadenylation (APA) during EMT...

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Bibliographic Details
Main Authors: Daniel P. Neumann, Katherine A. Pillman, B. Kate Dredge, Andrew G. Bert, Caroline A. Phillips, Rachael Lumb, Yesha Ramani, Cameron P. Bracken, Brett G. Hollier, Luke A. Selth, Traude H. Beilharz, Gregory J. Goodall, Philip A. Gregory
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:RNA Biology
Subjects:
Quaking
epithelial-mesenchymal transition
alternative polyadenylation
Crosslinked immunopreciptation (CLIP) sequencing
3’ untranslated region (3’UTR)
RNA binding protein (RBP)
Online Access:https://www.tandfonline.com/doi/10.1080/15476286.2023.2294222
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