The impact of glucocorticoid receptor transactivation on context-dependent cell migration dynamics

The impact of glucocorticoid receptor transactivation on context-dependent cell migration dynamics

Abstract The glucocorticoid receptor (GR) plays a significant role in breast cancer cell behaviour, although data on its effects are conflicting. The impact of GR agonist dexamethasone (dex) and antagonist mifepristone (mif) on oestrogen-positive (ER+) and triple-negative (TN) breast cancer cell lin...

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Main Authors: Szonja Polett Pósa, Éva Saskői, Lili Bársony, Lőrinc Pongor, Fanni Fekete, János Papp, Anikó Bozsik, Attila Patócs, Henriett Butz
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Glucocorticoid
Glucocorticoid receptor
Breast cancer
Migration
Transcriptome
Gene expression
Online Access:https://doi.org/10.1038/s41598-025-88666-1
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