Evaluation of Effectiveness of a New Kit of Reagents for Detection of Mutations Associated with Drug Resistance of Tuberculous Mycobacteria to Rifampicin and Isoniazid, by PCR according to Evidences of Clinical Trials

Evaluation of Effectiveness of a New Kit of Reagents for Detection of Mutations Associated with Drug Resistance of Tuberculous Mycobacteria to Rifampicin and Isoniazid, by PCR according to Evidences of Clinical Trials

The objective: to evalute effectiveness in clinical trials of the new kit of reagents of AmpliTest® MBT-Resist-I based on real-time PCR (RT-PCR) versus similar kits of reagent registered in Russia, to identify genetic markers of M. tuberculosis complex (MTB) resistance to rifampicin (RIF) and isonia...

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Bibliographic Details
Main Authors: Yu. L. Mikulovich, Yu. A. Savochkina, A. I. Zaytseva, A. E. Panova, A. S. Vinokurov, G. A. Shipulin
Format: Article
Language:Russian
Published: New Terra Publishing House 2023-08-01
Series:Туберкулез и болезни лёгких
Subjects:
copd
drug resistant mtb
genetic markers of resistance
rifampicin
isoniazid
real-time pcr
Online Access:https://www.tibl-journal.com/jour/article/view/1744
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