Epigenomic signatures of accelerated epigenetic aging are associated with congenital heart disease in newborns

Epigenomic signatures of accelerated epigenetic aging are associated with congenital heart disease in newborns

Abstract Background Congenital heart disease (CHD) lesions are the most common birth defects and despite advances in care, are associated with short- and long-term co-morbidities. The exact mechanisms that may influence outcomes in survivors with CHD remain unclear and are likely multi-factorial; ex...

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Bibliographic Details
Main Authors: Kristen Kocher, Julius Ngwa, Surajit Bhattacharya, Mary Donofrio, Catherine Limperopoulos, Nickie Andescavage
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medical Genomics
Subjects:
Congenital heart disease
DNA methylation
Epigenetic aging
Epigenomics
Online Access:https://doi.org/10.1186/s12920-025-02189-2
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