Corneal Endothelial Characteristics, Central Corneal Thickness, and Intraocular Pressure in a Population of Chinese Age-Related Cataract Patients

Purpose. To describe corneal endothelial characteristics, central corneal thickness, and intraocular pressure in a population of Chinese age-related cataract patients and to determine the effects of age, gender, hypertension, and body mass index (BMI). Methods. 1551 eyes were examined preoperatively...

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Main Authors: Yingmei Li, Zhentao Fu, Jian Liu, Miao Li, Yuguang Zhang, Xinyi Wu
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2017/9154626
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author Yingmei Li
Zhentao Fu
Jian Liu
Miao Li
Yuguang Zhang
Xinyi Wu
author_facet Yingmei Li
Zhentao Fu
Jian Liu
Miao Li
Yuguang Zhang
Xinyi Wu
author_sort Yingmei Li
collection DOAJ
description Purpose. To describe corneal endothelial characteristics, central corneal thickness, and intraocular pressure in a population of Chinese age-related cataract patients and to determine the effects of age, gender, hypertension, and body mass index (BMI). Methods. 1551 eyes were examined preoperatively. The parameters measured were endothelial cell density (CD), average cell area (CA), coefficient of variation (CV), cell hexagonality (HEX), central corneal thickness (CCT), intraocular pressure (IOP), and axial length (AL). Results. There were significant differences in CV and BMI between genders. There was a significant decrease in CD, CCT, and IOP and, conversely, an increase in CA and BMI with increasing age. The patients who suffered from hypertension had bigger CA, less CD, and lower HEX than the patients who did not suffer from hypertension. CD has a negative correlation with age and CV and a positive correlation with CCT, CCT has a positive association with CD and IOP, and IOP had a negative relationship with age and a positive relationship with CCT, CA, and HEX. Conclusions. Normative data for the corneal endothelium, central corneal thickness, and intraocular pressure in the normal age-related cataract patients are reported which will serve as a baseline for comparative studies about cataract.
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series Journal of Ophthalmology
spelling doaj-art-f905dfe2051d419cb4ff2ab70e5ae28f2025-02-03T01:02:12ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/91546269154626Corneal Endothelial Characteristics, Central Corneal Thickness, and Intraocular Pressure in a Population of Chinese Age-Related Cataract PatientsYingmei Li0Zhentao Fu1Jian Liu2Miao Li3Yuguang Zhang4Xinyi Wu5Department of Ophthalmology, The Second People’s Hospital of Jinan, No. 148 Jingyi Road, Jinan, Shandong 250001, ChinaAcademy of Preventive Medicine, Shandong University, Jinan, ChinaDepartment of Ophthalmology, The Second People’s Hospital of Jinan, No. 148 Jingyi Road, Jinan, Shandong 250001, ChinaDepartment of Ophthalmology, The Second People’s Hospital of Jinan, No. 148 Jingyi Road, Jinan, Shandong 250001, ChinaDepartment of Ophthalmology, The Second People’s Hospital of Jinan, No. 148 Jingyi Road, Jinan, Shandong 250001, ChinaDepartment of Ophthalmology, Qilu Hospital Affiliated Shandong University, Jinan, Shandong 250012, ChinaPurpose. To describe corneal endothelial characteristics, central corneal thickness, and intraocular pressure in a population of Chinese age-related cataract patients and to determine the effects of age, gender, hypertension, and body mass index (BMI). Methods. 1551 eyes were examined preoperatively. The parameters measured were endothelial cell density (CD), average cell area (CA), coefficient of variation (CV), cell hexagonality (HEX), central corneal thickness (CCT), intraocular pressure (IOP), and axial length (AL). Results. There were significant differences in CV and BMI between genders. There was a significant decrease in CD, CCT, and IOP and, conversely, an increase in CA and BMI with increasing age. The patients who suffered from hypertension had bigger CA, less CD, and lower HEX than the patients who did not suffer from hypertension. CD has a negative correlation with age and CV and a positive correlation with CCT, CCT has a positive association with CD and IOP, and IOP had a negative relationship with age and a positive relationship with CCT, CA, and HEX. Conclusions. Normative data for the corneal endothelium, central corneal thickness, and intraocular pressure in the normal age-related cataract patients are reported which will serve as a baseline for comparative studies about cataract.http://dx.doi.org/10.1155/2017/9154626
spellingShingle Yingmei Li
Zhentao Fu
Jian Liu
Miao Li
Yuguang Zhang
Xinyi Wu
Corneal Endothelial Characteristics, Central Corneal Thickness, and Intraocular Pressure in a Population of Chinese Age-Related Cataract Patients
Journal of Ophthalmology
title Corneal Endothelial Characteristics, Central Corneal Thickness, and Intraocular Pressure in a Population of Chinese Age-Related Cataract Patients
title_full Corneal Endothelial Characteristics, Central Corneal Thickness, and Intraocular Pressure in a Population of Chinese Age-Related Cataract Patients
title_fullStr Corneal Endothelial Characteristics, Central Corneal Thickness, and Intraocular Pressure in a Population of Chinese Age-Related Cataract Patients
title_full_unstemmed Corneal Endothelial Characteristics, Central Corneal Thickness, and Intraocular Pressure in a Population of Chinese Age-Related Cataract Patients
title_short Corneal Endothelial Characteristics, Central Corneal Thickness, and Intraocular Pressure in a Population of Chinese Age-Related Cataract Patients
title_sort corneal endothelial characteristics central corneal thickness and intraocular pressure in a population of chinese age related cataract patients
url http://dx.doi.org/10.1155/2017/9154626
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