Profile of Chlamydia vaccine research: A bibliometric analysis

Vaccination is the most effective measure to prevent Chlamydia infection. However, to date, no vaccine has successfully completed the rigorous clinical trial process and gained regulatory approval for use in clinical practice. Scholars have been working on a safe and effective Chlamydia vaccine. In...

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Main Authors: Xuemei Wang, Qian Wang, Yidan Gao, Lijuan Jiang, Lingli Tang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Human Vaccines & Immunotherapeutics
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Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2025.2459459
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author Xuemei Wang
Qian Wang
Yidan Gao
Lijuan Jiang
Lingli Tang
author_facet Xuemei Wang
Qian Wang
Yidan Gao
Lijuan Jiang
Lingli Tang
author_sort Xuemei Wang
collection DOAJ
description Vaccination is the most effective measure to prevent Chlamydia infection. However, to date, no vaccine has successfully completed the rigorous clinical trial process and gained regulatory approval for use in clinical practice. Scholars have been working on a safe and effective Chlamydia vaccine. In order to better grasp, the global frontiers and development trends in this field, a comprehensive bibliometric analysis was carried out. A total of 234 publications closely regarding Chlamydia vaccines were culled from the Web of Science Core Collection database, and the bibliometric information was then extracted with CiteSpace and VOSviewer software. After measurement analysis, the most influential papers were identified in this area, including highly cited papers, references with strong citation burst, and high co-citated papers. Vaccine has published the most literature on Chlamydia vaccines. Only scholars from 39 countries/regions have been engaged in studying Chlamydia vaccines. The USA is the most prolific country and has the highest collaborative strength. The current research area has focused on protective immunity and immunopathological response. Major outer membrane protein (MOMP) is the most common target vaccine antigen. This study reveals the status of literature and highlights emerging trends in this field, which helps researchers seek insights into this area and serve as a reference guide for further investigations.
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issn 2164-5515
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language English
publishDate 2025-12-01
publisher Taylor & Francis Group
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series Human Vaccines & Immunotherapeutics
spelling doaj-art-f8f157a3b4834814ac0a5472b2caa3f22025-02-05T09:38:03ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2025-12-0121110.1080/21645515.2025.2459459Profile of Chlamydia vaccine research: A bibliometric analysisXuemei Wang0Qian Wang1Yidan Gao2Lijuan Jiang3Lingli Tang4Department of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, ChinaDepartment of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, ChinaDepartment of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, ChinaDepartment of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, ChinaDepartment of Laboratory Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, ChinaVaccination is the most effective measure to prevent Chlamydia infection. However, to date, no vaccine has successfully completed the rigorous clinical trial process and gained regulatory approval for use in clinical practice. Scholars have been working on a safe and effective Chlamydia vaccine. In order to better grasp, the global frontiers and development trends in this field, a comprehensive bibliometric analysis was carried out. A total of 234 publications closely regarding Chlamydia vaccines were culled from the Web of Science Core Collection database, and the bibliometric information was then extracted with CiteSpace and VOSviewer software. After measurement analysis, the most influential papers were identified in this area, including highly cited papers, references with strong citation burst, and high co-citated papers. Vaccine has published the most literature on Chlamydia vaccines. Only scholars from 39 countries/regions have been engaged in studying Chlamydia vaccines. The USA is the most prolific country and has the highest collaborative strength. The current research area has focused on protective immunity and immunopathological response. Major outer membrane protein (MOMP) is the most common target vaccine antigen. This study reveals the status of literature and highlights emerging trends in this field, which helps researchers seek insights into this area and serve as a reference guide for further investigations.https://www.tandfonline.com/doi/10.1080/21645515.2025.2459459ChlamydiavaccinebibliometricCiteSpaceVosviewerMOMP
spellingShingle Xuemei Wang
Qian Wang
Yidan Gao
Lijuan Jiang
Lingli Tang
Profile of Chlamydia vaccine research: A bibliometric analysis
Human Vaccines & Immunotherapeutics
Chlamydia
vaccine
bibliometric
CiteSpace
Vosviewer
MOMP
title Profile of Chlamydia vaccine research: A bibliometric analysis
title_full Profile of Chlamydia vaccine research: A bibliometric analysis
title_fullStr Profile of Chlamydia vaccine research: A bibliometric analysis
title_full_unstemmed Profile of Chlamydia vaccine research: A bibliometric analysis
title_short Profile of Chlamydia vaccine research: A bibliometric analysis
title_sort profile of chlamydia vaccine research a bibliometric analysis
topic Chlamydia
vaccine
bibliometric
CiteSpace
Vosviewer
MOMP
url https://www.tandfonline.com/doi/10.1080/21645515.2025.2459459
work_keys_str_mv AT xuemeiwang profileofchlamydiavaccineresearchabibliometricanalysis
AT qianwang profileofchlamydiavaccineresearchabibliometricanalysis
AT yidangao profileofchlamydiavaccineresearchabibliometricanalysis
AT lijuanjiang profileofchlamydiavaccineresearchabibliometricanalysis
AT linglitang profileofchlamydiavaccineresearchabibliometricanalysis