mTOR inhibition sensitizes T-ALL cells to Venetoclax through engagement of the integrated stress response
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-08-01
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| Series: | Signal Transduction and Targeted Therapy |
| Online Access: | https://doi.org/10.1038/s41392-025-02368-8 |
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| _version_ | 1849389479031209984 |
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| author | Loredana Urso Irene Bertazzolo Alberto Corradin Micol Silic-Benussi Sonia A. Minuzzo Donna M. D’Agostino Vincenzo Ciminale |
| author_facet | Loredana Urso Irene Bertazzolo Alberto Corradin Micol Silic-Benussi Sonia A. Minuzzo Donna M. D’Agostino Vincenzo Ciminale |
| author_sort | Loredana Urso |
| collection | DOAJ |
| format | Article |
| id | doaj-art-f8e93e4bd4294cc19245c19351e2c37e |
| institution | Kabale University |
| issn | 2059-3635 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Signal Transduction and Targeted Therapy |
| spelling | doaj-art-f8e93e4bd4294cc19245c19351e2c37e2025-08-20T03:41:57ZengNature Publishing GroupSignal Transduction and Targeted Therapy2059-36352025-08-011011410.1038/s41392-025-02368-8mTOR inhibition sensitizes T-ALL cells to Venetoclax through engagement of the integrated stress responseLoredana Urso0Irene Bertazzolo1Alberto Corradin2Micol Silic-Benussi3Sonia A. Minuzzo4Donna M. D’Agostino5Vincenzo Ciminale6Veneto Institute of Oncology IOV – IRCCSUniversity of PadovaVeneto Institute of Oncology IOV – IRCCSVeneto Institute of Oncology IOV – IRCCSUniversity of PadovaVeneto Institute of Oncology IOV – IRCCSVeneto Institute of Oncology IOV – IRCCShttps://doi.org/10.1038/s41392-025-02368-8 |
| spellingShingle | Loredana Urso Irene Bertazzolo Alberto Corradin Micol Silic-Benussi Sonia A. Minuzzo Donna M. D’Agostino Vincenzo Ciminale mTOR inhibition sensitizes T-ALL cells to Venetoclax through engagement of the integrated stress response Signal Transduction and Targeted Therapy |
| title | mTOR inhibition sensitizes T-ALL cells to Venetoclax through engagement of the integrated stress response |
| title_full | mTOR inhibition sensitizes T-ALL cells to Venetoclax through engagement of the integrated stress response |
| title_fullStr | mTOR inhibition sensitizes T-ALL cells to Venetoclax through engagement of the integrated stress response |
| title_full_unstemmed | mTOR inhibition sensitizes T-ALL cells to Venetoclax through engagement of the integrated stress response |
| title_short | mTOR inhibition sensitizes T-ALL cells to Venetoclax through engagement of the integrated stress response |
| title_sort | mtor inhibition sensitizes t all cells to venetoclax through engagement of the integrated stress response |
| url | https://doi.org/10.1038/s41392-025-02368-8 |
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