The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins.

The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins.

SARS Coronavirus 2 (SARS-CoV-2) emerged in late 2019, leading to the Coronavirus Disease 2019 (COVID-19) pandemic that continues to cause significant global mortality in human populations. Given its sequence similarity to SARS-CoV, as well as related coronaviruses circulating in bats, SARS-CoV-2 is...

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Main Authors: Carina Conceicao, Nazia Thakur, Stacey Human, James T Kelly, Leanne Logan, Dagmara Bialy, Sushant Bhat, Phoebe Stevenson-Leggett, Adrian K Zagrajek, Philippa Hollinghurst, Michal Varga, Christina Tsirigoti, Matthew Tully, Chris Chiu, Katy Moffat, Adrian Paul Silesian, John A Hammond, Helena J Maier, Erica Bickerton, Holly Shelton, Isabelle Dietrich, Stephen C Graham, Dalan Bailey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001016&type=printable
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