Complete or incomplete revascularization in patients with left main culprit lesion acute myocardial infarction with multivessel disease: a retrospective observational study
Background Complete revascularization has demonstrated better outcomes in patients with acute myocardial infarction (AMI) and multivessel disease. However, in the case of left main (LM) culprit lesion AMI with multivessel disease, there is limited evidence to suggest that complete revascularization...
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Yeungnam University College of Medicine, Yeungnam University Institute Medical Science
2025-02-01
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| Series: | Journal of Yeungnam Medical Science |
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| author | Sun Oh Kim Hong-Ju Kim Jong-Il Park Kang-Un Choi Jong-Ho Nam Chan-Hee Lee Jang-Won Son Jong-Seon Park Sung-Ho Her Ki-Yuk Chang Tae-Hoon Ahn Myung-Ho Jeong Seung-Woon Rha Hyo-Soo Kim Hyeon-Cheol Gwon In-Whan Seong Kyung-Kuk Hwang Seung-Ho Hur Kwang-Soo Cha Seok-Kyu Oh Jei-Keon Chae Ung Kim |
| author_facet | Sun Oh Kim Hong-Ju Kim Jong-Il Park Kang-Un Choi Jong-Ho Nam Chan-Hee Lee Jang-Won Son Jong-Seon Park Sung-Ho Her Ki-Yuk Chang Tae-Hoon Ahn Myung-Ho Jeong Seung-Woon Rha Hyo-Soo Kim Hyeon-Cheol Gwon In-Whan Seong Kyung-Kuk Hwang Seung-Ho Hur Kwang-Soo Cha Seok-Kyu Oh Jei-Keon Chae Ung Kim |
| author_sort | Sun Oh Kim |
| collection | DOAJ |
| description | Background Complete revascularization has demonstrated better outcomes in patients with acute myocardial infarction (AMI) and multivessel disease. However, in the case of left main (LM) culprit lesion AMI with multivessel disease, there is limited evidence to suggest that complete revascularization is better. Methods We reviewed 16,831 patients in the Korea Acute Myocardial Infarction Registry who were treated from July 2016 to June 2020, and 399 patients were enrolled with LM culprit lesion AMI treated with percutaneous coronary intervention. We categorized the patients as those treated with complete revascularization (n=295) or incomplete revascularization (n=104). The study endpoint was major adverse cardiac and cerebrovascular events (MACCE), a composite of all-cause death, myocardial infarction, ischemia-driven revascularization, stent thrombosis, and stroke. We performed propensity score matching (PSM) and analyzed the incidence of MACCE at 1 year. Results After PSM, the two groups were well balanced. There was no significant difference between the two groups in MACCE at 1 year (12.1% vs. 15.2%; hazard ratio, 1.28; 95% confidence interval, 0.60–2.74; p=0.524) after PSM. The components of MACCE and major bleeding were also not significantly different. Conclusion There was no significant difference in clinical outcomes between the groups treated with complete or incomplete revascularization for LM culprit lesion AMI with multivessel disease. |
| format | Article |
| id | doaj-art-f8ac26bd3a6d433aa84ec5f383050cc8 |
| institution | Kabale University |
| issn | 2799-8010 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Yeungnam University College of Medicine, Yeungnam University Institute Medical Science |
| record_format | Article |
| series | Journal of Yeungnam Medical Science |
| spelling | doaj-art-f8ac26bd3a6d433aa84ec5f383050cc82025-02-11T06:26:38ZengYeungnam University College of Medicine, Yeungnam University Institute Medical ScienceJournal of Yeungnam Medical Science2799-80102025-02-014210.12701/jyms.2025.42.182880Complete or incomplete revascularization in patients with left main culprit lesion acute myocardial infarction with multivessel disease: a retrospective observational studySun Oh Kim0Hong-Ju Kim1Jong-Il Park2Kang-Un Choi3Jong-Ho Nam4Chan-Hee Lee5Jang-Won Son6Jong-Seon Park7Sung-Ho Her8Ki-Yuk Chang9Tae-Hoon Ahn10Myung-Ho Jeong11Seung-Woon Rha12Hyo-Soo Kim13Hyeon-Cheol Gwon14In-Whan Seong15Kyung-Kuk Hwang16Seung-Ho Hur17Kwang-Soo Cha18Seok-Kyu Oh19Jei-Keon Chae20Ung Kim21 Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea Division of Cardiology, Department of Internal Medicine, St.Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea Division of Cardiology, Department of Internal Medicine, The Catholic University of Korea, Seoul St. Mary’s Hospital, Seoul, Korea Division of Cardiology, Department of Internal Medicine, Korea University Anam Hospital, Seoul, Korea Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea Division of Cardiology, Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea Division of Cardiology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan Universtiy College of Medicine, Seoul, Korea Division of Cardiology, Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea Division of Cardiology, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea Division of Cardiology, Department of Internal Medicine, Pusan National University Hospital, Busan, Korea Division of Cardiology, Department of Internal Medicine, Wonkwang University Hospital, Iksan, Korea Division of Cardiology, Department of Internal Medicine, Chonbuk National University Hospital, Jeonju, Korea Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, KoreaBackground Complete revascularization has demonstrated better outcomes in patients with acute myocardial infarction (AMI) and multivessel disease. However, in the case of left main (LM) culprit lesion AMI with multivessel disease, there is limited evidence to suggest that complete revascularization is better. Methods We reviewed 16,831 patients in the Korea Acute Myocardial Infarction Registry who were treated from July 2016 to June 2020, and 399 patients were enrolled with LM culprit lesion AMI treated with percutaneous coronary intervention. We categorized the patients as those treated with complete revascularization (n=295) or incomplete revascularization (n=104). The study endpoint was major adverse cardiac and cerebrovascular events (MACCE), a composite of all-cause death, myocardial infarction, ischemia-driven revascularization, stent thrombosis, and stroke. We performed propensity score matching (PSM) and analyzed the incidence of MACCE at 1 year. Results After PSM, the two groups were well balanced. There was no significant difference between the two groups in MACCE at 1 year (12.1% vs. 15.2%; hazard ratio, 1.28; 95% confidence interval, 0.60–2.74; p=0.524) after PSM. The components of MACCE and major bleeding were also not significantly different. Conclusion There was no significant difference in clinical outcomes between the groups treated with complete or incomplete revascularization for LM culprit lesion AMI with multivessel disease.http://www.e-jyms.org/upload/pdf/jyms-2025-42-18.pdfleft main diseasemultivessel diseasemyocardial infarctionpercutaneous coronary revascularization |
| spellingShingle | Sun Oh Kim Hong-Ju Kim Jong-Il Park Kang-Un Choi Jong-Ho Nam Chan-Hee Lee Jang-Won Son Jong-Seon Park Sung-Ho Her Ki-Yuk Chang Tae-Hoon Ahn Myung-Ho Jeong Seung-Woon Rha Hyo-Soo Kim Hyeon-Cheol Gwon In-Whan Seong Kyung-Kuk Hwang Seung-Ho Hur Kwang-Soo Cha Seok-Kyu Oh Jei-Keon Chae Ung Kim Complete or incomplete revascularization in patients with left main culprit lesion acute myocardial infarction with multivessel disease: a retrospective observational study Journal of Yeungnam Medical Science left main disease multivessel disease myocardial infarction percutaneous coronary revascularization |
| title | Complete or incomplete revascularization in patients with left main culprit lesion acute myocardial infarction with multivessel disease: a retrospective observational study |
| title_full | Complete or incomplete revascularization in patients with left main culprit lesion acute myocardial infarction with multivessel disease: a retrospective observational study |
| title_fullStr | Complete or incomplete revascularization in patients with left main culprit lesion acute myocardial infarction with multivessel disease: a retrospective observational study |
| title_full_unstemmed | Complete or incomplete revascularization in patients with left main culprit lesion acute myocardial infarction with multivessel disease: a retrospective observational study |
| title_short | Complete or incomplete revascularization in patients with left main culprit lesion acute myocardial infarction with multivessel disease: a retrospective observational study |
| title_sort | complete or incomplete revascularization in patients with left main culprit lesion acute myocardial infarction with multivessel disease a retrospective observational study |
| topic | left main disease multivessel disease myocardial infarction percutaneous coronary revascularization |
| url | http://www.e-jyms.org/upload/pdf/jyms-2025-42-18.pdf |
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