A Lucknolide Derivative Induces Mitochondrial ROS-Mediated G2/M Arrest and Apoptotic Cell Death in B16F10 Mouse Melanoma Cells

A Lucknolide Derivative Induces Mitochondrial ROS-Mediated G2/M Arrest and Apoptotic Cell Death in B16F10 Mouse Melanoma Cells

Melanoma is an aggressive skin cancer with a high risk of cancer-related deaths, and inducing apoptosis in melanoma cells is a promising therapeutic strategy. This study investigates the anti-tumor potential of a novel lucknolide derivative LA-UC as a therapeutic candidate for melanoma. Lucknolide A...

Full description

Saved in:
Bibliographic Details
Main Authors: Jae Hyeop Lee, Byeoung-Kyu Choi, Minsoo Kim, Hee Jae Shin, Sun Joo Park
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Marine Drugs
Subjects:
lucknolide derivative
marine Streptomyces
melanoma
mitochondrial ROS
apoptosis
anti-tumor
Online Access:https://www.mdpi.com/1660-3397/22/12/533
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items