Sex‐Dependent Phenotypic Variability of an SCN5A Mutation: Brugada Syndrome and Sick Sinus Syndrome

Sex‐Dependent Phenotypic Variability of an SCN5A Mutation: Brugada Syndrome and Sick Sinus Syndrome

Background Brugada syndrome (BS) is known to be 9 times more prevalent in males than females. However, little is known about the development of sick sinus syndrome in female members with familial BS. Methods and Results Familial BS patients and family members, both from our institutions and collabor...

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Main Authors: Yoshiyasu Aizawa, Taishi Fujisawa, Yoshinori Katsumata, Shun Kohsaka, Akira Kunitomi, Seiko Ohno, Keiko Sonoda, Hidemori Hayashi, Rintaro Hojo, Seiji Fukamizu, Satoshi Nagase, Shogo Ito, Kazuaki Nakajima, Takahiko Nishiyama, Takehiro Kimura, Yasuo Kurita, Yoshiko Furukawa, Seiji Takatsuki, Satoshi Ogawa, Yuji Nakazato, Masataka Sumiyoshi, Kenjiro Kosaki, Minoru Horie, Keiichi Fukuda
Format: Article
Language:English
Published: Wiley 2018-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Brugada syndrome
SCN5A
sex
sick sinus syndrome
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.009387
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