Dendritic Cell Vaccine Harboring Inactivated Mycobacteria Induces Immune Protection Against Tuberculosis in Murine Models and is Well Tolerated in Humans

Dendritic Cell Vaccine Harboring Inactivated Mycobacteria Induces Immune Protection Against Tuberculosis in Murine Models and is Well Tolerated in Humans

The limited success of tuberculosis (TB) control measures reflects the inadequacy of Bacille Calmette‐Guérin (BCG), the only licensed TB vaccine. There is a recent resurgence of interest in intravenous administration of BCG. However, direct injection of live BCG bacteria into the bloodstream of huma...

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Bibliographic Details
Main Authors: Zhidong Hu, Xuhui Liu, Jing Wang, Ling Gu, Zhenyan Chen, Lu Xia, Heng Yang, Jinchuan Xu, Xuejiao Huang, Huiling Wang, Shuihua Lu, Xiao‐Yong Fan
Format: Article
Language:English
Published: Wiley-VCH 2025-02-01
Series:Small Science
Subjects:
dendritic cells
macrophages
T cells
tuberculosis
vaccines
Online Access:https://doi.org/10.1002/smsc.202400355
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