Scalable eQTL mapping using single-nucleus RNA-sequencing of recombined gametes from a small number of individuals.

Scalable eQTL mapping using single-nucleus RNA-sequencing of recombined gametes from a small number of individuals.

Phenotypic differences between individuals of a species are often caused by differences in gene expression, which are in turn caused by genetic variation. Expression quantitative trait locus (eQTL) analysis is a methodology by which we can identify such causal variants. Scaling eQTL analysis is cost...

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Bibliographic Details
Main Authors: Matthew T Parker, Samija Amar, José A Campoy, Kristin Krause, Sergio Tusso, Magdalena Marek, Bruno Huettel, Korbinian Schneeberger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-04-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3003085
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