Fluid flow impacts endothelial-monocyte interactions in a model of vascular inflammatory fibrosis

Fluid flow impacts endothelial-monocyte interactions in a model of vascular inflammatory fibrosis

Abstract The aberrant vascular response associated with tendon injury results in circulating immune cell infiltration and a chronic inflammatory feedback loop leading to poor healing outcomes. Studying this dysregulated tendon repair response in human pathophysiology has been historically challengin...

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Bibliographic Details
Main Authors:	Isabelle Linares, Kaihua Chen, Ava Saffren, Mehran Mansouri, Vinay V. Abhyankar, Benjamin L. Miller, Stefano Begolo, Hani A. Awad, James L. McGrath
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-01-01
Series:	Scientific Reports
Subjects:	Fluidic shear stress Vascular barriers Monocyte transmigration Inflammation Fibrosis Microphysiological systems
Online Access:	https://doi.org/10.1038/s41598-025-85987-z
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