Seq2scFv: a toolkit for the comprehensive analysis of display libraries from long-read sequencing platforms

Seq2scFv: a toolkit for the comprehensive analysis of display libraries from long-read sequencing platforms

Antibodies have emerged as the leading class of biotherapeutics, yet traditional screening methods face significant time and resource challenges in identifying lead candidates. Integrating high-throughput sequencing with computational approaches marks a pivotal advancement in antibody discovery, exp...

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Bibliographic Details
Main Authors: Marianne Bachmann Salvy, Luca Santuari, Emanuel Schmid-Siegert, Nikolaos Lykoskoufis, Ioannis Xenarios, Bulak Arpat
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:mAbs
Subjects:
Antibody discovery
long-read sequencing
PacBio
phage display
scFvs
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2024.2408344
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