Botulinum toxin A as a treatment modality for acute acquired comitant esotropia – An Indian perspective

Purpose: To analyze the outcomes of botulinum toxin A injection in acute acquired comitant esotropia (AACE). Methods: This is a retrospective study that included cases diagnosed as AACE between January 2022 and February 2023. Patients who were treated with Botox and completed a minimum 3 months foll...

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Main Authors: Akshay Badakere, Vibha Badrinath, Hennaav Kaur Dhillon, Abinaya Valliappan, Viswanathan Natarajan, Sumita Agarkar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-02-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.4103/IJO.IJO_2198_23
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author Akshay Badakere
Vibha Badrinath
Hennaav Kaur Dhillon
Abinaya Valliappan
Viswanathan Natarajan
Sumita Agarkar
author_facet Akshay Badakere
Vibha Badrinath
Hennaav Kaur Dhillon
Abinaya Valliappan
Viswanathan Natarajan
Sumita Agarkar
author_sort Akshay Badakere
collection DOAJ
description Purpose: To analyze the outcomes of botulinum toxin A injection in acute acquired comitant esotropia (AACE). Methods: This is a retrospective study that included cases diagnosed as AACE between January 2022 and February 2023. Patients who were treated with Botox and completed a minimum 3 months follow-up were included in the study. All the patients underwent a complete ophthalmic, orthoptic examination and neuroimaging. The effects of age, onset of esotropia, screen time, deviation pre injection, mode of injection (transconjunctival/ open sky) and whether injection was administered in one/both eyes on successful outcome were analysed. Results: Twenty-seven patients (20 male, seven female) were included in the study. The median age was 10 years. The median deviation for distance and near preinjection was 35 and 40 prism diopters, respectively. Complete resolution of symptoms was noted in 18 patients (66.6%). Four patients needed prisms, two required repeat injections, and one each needed surgery and divergence therapy. Six patients developed ptosis. None of the risk factors seemed to affect outcomes. Conclusion: Botulinum toxin injected into the medial rectus is a safe and viable option for AACE. Preinjection counseling about ptosis, recurrence needing prisms, reinjection, or surgery is important.
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institution Kabale University
issn 0301-4738
1998-3689
language English
publishDate 2025-02-01
publisher Wolters Kluwer Medknow Publications
record_format Article
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spelling doaj-art-f844255be7bc4cf79d68e5d7a91698bf2025-02-06T05:39:35ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892025-02-0173222823010.4103/IJO.IJO_2198_23Botulinum toxin A as a treatment modality for acute acquired comitant esotropia – An Indian perspectiveAkshay BadakereVibha BadrinathHennaav Kaur DhillonAbinaya ValliappanViswanathan NatarajanSumita AgarkarPurpose: To analyze the outcomes of botulinum toxin A injection in acute acquired comitant esotropia (AACE). Methods: This is a retrospective study that included cases diagnosed as AACE between January 2022 and February 2023. Patients who were treated with Botox and completed a minimum 3 months follow-up were included in the study. All the patients underwent a complete ophthalmic, orthoptic examination and neuroimaging. The effects of age, onset of esotropia, screen time, deviation pre injection, mode of injection (transconjunctival/ open sky) and whether injection was administered in one/both eyes on successful outcome were analysed. Results: Twenty-seven patients (20 male, seven female) were included in the study. The median age was 10 years. The median deviation for distance and near preinjection was 35 and 40 prism diopters, respectively. Complete resolution of symptoms was noted in 18 patients (66.6%). Four patients needed prisms, two required repeat injections, and one each needed surgery and divergence therapy. Six patients developed ptosis. None of the risk factors seemed to affect outcomes. Conclusion: Botulinum toxin injected into the medial rectus is a safe and viable option for AACE. Preinjection counseling about ptosis, recurrence needing prisms, reinjection, or surgery is important.https://journals.lww.com/10.4103/IJO.IJO_2198_23acquiredacutebotulinum toxinesotropiasurgery
spellingShingle Akshay Badakere
Vibha Badrinath
Hennaav Kaur Dhillon
Abinaya Valliappan
Viswanathan Natarajan
Sumita Agarkar
Botulinum toxin A as a treatment modality for acute acquired comitant esotropia – An Indian perspective
Indian Journal of Ophthalmology
acquired
acute
botulinum toxin
esotropia
surgery
title Botulinum toxin A as a treatment modality for acute acquired comitant esotropia – An Indian perspective
title_full Botulinum toxin A as a treatment modality for acute acquired comitant esotropia – An Indian perspective
title_fullStr Botulinum toxin A as a treatment modality for acute acquired comitant esotropia – An Indian perspective
title_full_unstemmed Botulinum toxin A as a treatment modality for acute acquired comitant esotropia – An Indian perspective
title_short Botulinum toxin A as a treatment modality for acute acquired comitant esotropia – An Indian perspective
title_sort botulinum toxin a as a treatment modality for acute acquired comitant esotropia an indian perspective
topic acquired
acute
botulinum toxin
esotropia
surgery
url https://journals.lww.com/10.4103/IJO.IJO_2198_23
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AT hennaavkaurdhillon botulinumtoxinaasatreatmentmodalityforacuteacquiredcomitantesotropiaanindianperspective
AT abinayavalliappan botulinumtoxinaasatreatmentmodalityforacuteacquiredcomitantesotropiaanindianperspective
AT viswanathannatarajan botulinumtoxinaasatreatmentmodalityforacuteacquiredcomitantesotropiaanindianperspective
AT sumitaagarkar botulinumtoxinaasatreatmentmodalityforacuteacquiredcomitantesotropiaanindianperspective