A Case of Listeria Monocytogenes Brain Abscess with a Clinical Presentation Mimicking Stroke

Purpose: Kidney transplant recipients are at a high risk of both stroke and infection. We report this case to inform readers of the possibility of the occurrence of Listeria monocytogenes brain abscess despite treatment with low dose trimethoprim–sulfamethoxazole (TMP/SMX). Case Report: A 62-year-ol...

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Main Authors: Ya-Chun Chu, Nai-Ching Chen, Chien-Liang Chen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Acta Neurologica Taiwanica
Subjects:
Online Access:https://journals.lww.com/10.4103//ANT.33-1_111_0066
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author Ya-Chun Chu
Nai-Ching Chen
Chien-Liang Chen
author_facet Ya-Chun Chu
Nai-Ching Chen
Chien-Liang Chen
author_sort Ya-Chun Chu
collection DOAJ
description Purpose: Kidney transplant recipients are at a high risk of both stroke and infection. We report this case to inform readers of the possibility of the occurrence of Listeria monocytogenes brain abscess despite treatment with low dose trimethoprim–sulfamethoxazole (TMP/SMX). Case Report: A 62-year-old man presented to our hospital with right facial palsy, left arm and leg weakness, and mild fever; he was diagnosed with a stroke in the emergency room. The patient had a history of cadaveric renal transplantation 2 years prior, for which he was prescribed tacrolimus- based immunosuppressive drugs. Multiple myeloma was diagnosed 18 months after renal transplant. He was treated with bortezomib and steroids for the multiple myeloma, and low-dose TMP/SMX for pneumocystis prophylaxis. A listeria brain abscess was diagnosed based on a comprehensive medical history, magnetic resonance images, positive blood culture, and brain biopsy. He underwent ampicillin therapy and achieved full recovery after a 3-month follow-up period. Conclusion: Physicians should monitor unusual stroke symptoms and consider Listeria brain abscess as a differential diagnosis. This case suggests that listeria brain abscesses can potentially cause temporary neurological deficits akin to a stroke, despite TMP/SMX prophylaxis, but these symptoms resolve without necessitating surgical intervention.
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spelling doaj-art-f8312dcac6f94039b877d2e8a88891df2025-08-20T03:25:59ZengWolters Kluwer Medknow PublicationsActa Neurologica Taiwanica1028-768X2024-01-01331303310.4103//ANT.33-1_111_0066A Case of Listeria Monocytogenes Brain Abscess with a Clinical Presentation Mimicking StrokeYa-Chun ChuNai-Ching ChenChien-Liang ChenPurpose: Kidney transplant recipients are at a high risk of both stroke and infection. We report this case to inform readers of the possibility of the occurrence of Listeria monocytogenes brain abscess despite treatment with low dose trimethoprim–sulfamethoxazole (TMP/SMX). Case Report: A 62-year-old man presented to our hospital with right facial palsy, left arm and leg weakness, and mild fever; he was diagnosed with a stroke in the emergency room. The patient had a history of cadaveric renal transplantation 2 years prior, for which he was prescribed tacrolimus- based immunosuppressive drugs. Multiple myeloma was diagnosed 18 months after renal transplant. He was treated with bortezomib and steroids for the multiple myeloma, and low-dose TMP/SMX for pneumocystis prophylaxis. A listeria brain abscess was diagnosed based on a comprehensive medical history, magnetic resonance images, positive blood culture, and brain biopsy. He underwent ampicillin therapy and achieved full recovery after a 3-month follow-up period. Conclusion: Physicians should monitor unusual stroke symptoms and consider Listeria brain abscess as a differential diagnosis. This case suggests that listeria brain abscesses can potentially cause temporary neurological deficits akin to a stroke, despite TMP/SMX prophylaxis, but these symptoms resolve without necessitating surgical intervention.https://journals.lww.com/10.4103//ANT.33-1_111_0066listeria monocytogeneslisteriosisbrain abscessstroke
spellingShingle Ya-Chun Chu
Nai-Ching Chen
Chien-Liang Chen
A Case of Listeria Monocytogenes Brain Abscess with a Clinical Presentation Mimicking Stroke
Acta Neurologica Taiwanica
listeria monocytogenes
listeriosis
brain abscess
stroke
title A Case of Listeria Monocytogenes Brain Abscess with a Clinical Presentation Mimicking Stroke
title_full A Case of Listeria Monocytogenes Brain Abscess with a Clinical Presentation Mimicking Stroke
title_fullStr A Case of Listeria Monocytogenes Brain Abscess with a Clinical Presentation Mimicking Stroke
title_full_unstemmed A Case of Listeria Monocytogenes Brain Abscess with a Clinical Presentation Mimicking Stroke
title_short A Case of Listeria Monocytogenes Brain Abscess with a Clinical Presentation Mimicking Stroke
title_sort case of listeria monocytogenes brain abscess with a clinical presentation mimicking stroke
topic listeria monocytogenes
listeriosis
brain abscess
stroke
url https://journals.lww.com/10.4103//ANT.33-1_111_0066
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AT yachunchu caseoflisteriamonocytogenesbrainabscesswithaclinicalpresentationmimickingstroke
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