The effect of chloroquine on cervical cancer via the PI3K/AKT/MDM2 pathway

The effect of chloroquine on cervical cancer via the PI3K/AKT/MDM2 pathway

Abstract Background Cervical cancer (CC), the most prevalent malignant tumor in the female reproductive system, is characterized by its high incidence and mortality rates. Chloroquine(CQ), a 4-aminoquinoline drug originally used to prevent and treat malaria, has gained recognition as an adjuvant ant...

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Main Authors: Dandan Xu, Chenyang Hou, Jianliang Chang, Shuaibo Yang, Zhicong Yang, Zelong Yuan, Jingqi Li, Shuqin Liu, Yaqun Liu, Yingpeng Su, Peng Gao, Xiaojuan Liu
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
Chloroquine
Cervical Cancer
PI3K/AKT
MDM2
Apoptosis
Online Access:https://doi.org/10.1007/s12672-025-02939-9
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https://doi.org/10.1007/s12672-025-02939-9

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