Prognostic Value of Glomerular Filtration Rate in Diabetic Patients with Acute Myocardial Infarction
<p><strong>Background</strong>: low glomerular filtration rate is a known poor prognostic factor in acute coronary syndrome, particularly when associated with diabetes mellitus.<br /><strong>Objective</strong>: to determine the prognostic value of glomerular filtr...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Spanish |
| Published: |
Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2015-11-01
|
| Series: | Medisur |
| Subjects: | |
| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/3032 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832577152639303680 |
|---|---|
| author | Ailed Elena Rodríguez Jiménez |
| author_facet | Ailed Elena Rodríguez Jiménez |
| author_sort | Ailed Elena Rodríguez Jiménez |
| collection | DOAJ |
| description | <p><strong>Background</strong>: low glomerular filtration rate is a known poor prognostic factor in acute coronary syndrome, particularly when associated with diabetes mellitus.<br /><strong>Objective</strong>: to determine the prognostic value of glomerular filtration rate in hospitalized diabetic patients with acute ST-segment elevation myocardial infarction.<br /><strong>Methods</strong>: a case-series study was conducted in 68 diabetic patients with acute ST-segment elevation myocardial infarction admitted to the Camilo Cienfuegos Hospital in Sancti Spiritus from January 2012 to December 2013. The glomerular filtration rate on admission was estimated using the Cockcroft-Gault <em>equation</em>. Cardiovascular risk factors, clinical and laboratory variables, the ejection fraction and hospital mortality were analyzed.<br /><strong>Results</strong>: low glomerular filtration rate was associated with a <em>left</em><em> </em><em>ventricular</em><em> </em><em>ejection</em><em> </em><em>fraction</em> <45% at discharge (p = 0.0060) and cardiac complications including arrhythmias, <em>atrioventricular</em><em> </em><em>conduction</em><em> </em><em>disturbances</em>, reinfarction, postinfarction angina and Killip class ≥ III (p = 0.0000). It was also associated with increased mortality and lower <em>reperfusion</em><em> </em><em>rates</em>.<strong><br />Conclusions</strong>: estimating the glomerular filtration rate in diabetic patients with acute coronary syndrome at the time of admission provides significant information for prognosis in the acute phase, even in those with normal creatinine values. A glomerular filtration rate less than 53 mL/min increases the risk of suffering an adverse event during hospitalization eight times.</p> |
| format | Article |
| id | doaj-art-f7dc5f0128c54eaaa7ac1570c9723e14 |
| institution | Kabale University |
| issn | 1727-897X |
| language | Spanish |
| publishDate | 2015-11-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj-art-f7dc5f0128c54eaaa7ac1570c9723e142025-01-30T21:28:49ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2015-11-011356306401247Prognostic Value of Glomerular Filtration Rate in Diabetic Patients with Acute Myocardial InfarctionAiled Elena Rodríguez Jiménez0Hospital Provincial Universitario Camilo Cienfuegos Gorriarán, Sancti Spíritus<p><strong>Background</strong>: low glomerular filtration rate is a known poor prognostic factor in acute coronary syndrome, particularly when associated with diabetes mellitus.<br /><strong>Objective</strong>: to determine the prognostic value of glomerular filtration rate in hospitalized diabetic patients with acute ST-segment elevation myocardial infarction.<br /><strong>Methods</strong>: a case-series study was conducted in 68 diabetic patients with acute ST-segment elevation myocardial infarction admitted to the Camilo Cienfuegos Hospital in Sancti Spiritus from January 2012 to December 2013. The glomerular filtration rate on admission was estimated using the Cockcroft-Gault <em>equation</em>. Cardiovascular risk factors, clinical and laboratory variables, the ejection fraction and hospital mortality were analyzed.<br /><strong>Results</strong>: low glomerular filtration rate was associated with a <em>left</em><em> </em><em>ventricular</em><em> </em><em>ejection</em><em> </em><em>fraction</em> <45% at discharge (p = 0.0060) and cardiac complications including arrhythmias, <em>atrioventricular</em><em> </em><em>conduction</em><em> </em><em>disturbances</em>, reinfarction, postinfarction angina and Killip class ≥ III (p = 0.0000). It was also associated with increased mortality and lower <em>reperfusion</em><em> </em><em>rates</em>.<strong><br />Conclusions</strong>: estimating the glomerular filtration rate in diabetic patients with acute coronary syndrome at the time of admission provides significant information for prognosis in the acute phase, even in those with normal creatinine values. A glomerular filtration rate less than 53 mL/min increases the risk of suffering an adverse event during hospitalization eight times.</p>http://medisur.sld.cu/index.php/medisur/article/view/3032tasa de filtración glomerularpronósticoinfarto del miocardiodiabetes mellitus |
| spellingShingle | Ailed Elena Rodríguez Jiménez Prognostic Value of Glomerular Filtration Rate in Diabetic Patients with Acute Myocardial Infarction Medisur tasa de filtración glomerular pronóstico infarto del miocardio diabetes mellitus |
| title | Prognostic Value of Glomerular Filtration Rate in Diabetic Patients with Acute Myocardial Infarction |
| title_full | Prognostic Value of Glomerular Filtration Rate in Diabetic Patients with Acute Myocardial Infarction |
| title_fullStr | Prognostic Value of Glomerular Filtration Rate in Diabetic Patients with Acute Myocardial Infarction |
| title_full_unstemmed | Prognostic Value of Glomerular Filtration Rate in Diabetic Patients with Acute Myocardial Infarction |
| title_short | Prognostic Value of Glomerular Filtration Rate in Diabetic Patients with Acute Myocardial Infarction |
| title_sort | prognostic value of glomerular filtration rate in diabetic patients with acute myocardial infarction |
| topic | tasa de filtración glomerular pronóstico infarto del miocardio diabetes mellitus |
| url | http://medisur.sld.cu/index.php/medisur/article/view/3032 |
| work_keys_str_mv | AT ailedelenarodriguezjimenez prognosticvalueofglomerularfiltrationrateindiabeticpatientswithacutemyocardialinfarction |