Epithelioid trophoblastic tumor: Clinical presentation, diagnosis, and treatment
Epithelioid trophoblastic tumor (ETT) is a rare form of trophoblastic disease, which is characterized by high malignancy and a number of diagnostic features: a long interval between the last pregnancy and labor and the onset of the disease; a visual pattern at gynecological examination, relatively l...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2014-08-01
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| Series: | Опухоли женской репродуктивной системы |
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| Online Access: | https://ojrs.abvpress.ru/ojrs/article/view/236 |
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| author | D. A. Lisayev B. O. Toloknov E. E. Makhova I. V. Markina |
| author_facet | D. A. Lisayev B. O. Toloknov E. E. Makhova I. V. Markina |
| author_sort | D. A. Lisayev |
| collection | DOAJ |
| description | Epithelioid trophoblastic tumor (ETT) is a rare form of trophoblastic disease, which is characterized by high malignancy and a number of diagnostic features: a long interval between the last pregnancy and labor and the onset of the disease; a visual pattern at gynecological examination, relatively low β-chorionic gonadotropin (CG) levels, as well as the diffuse expression of cytokeratins-7 (+++) and -18 (+++), р63 (nuclear ++), E-cadherin (+++), EGFR (+), and CD-117(++) by tumor cells, as determined by immunohistochemical assay, and focal expression of CG (++) and PLAP (+) by these cells. |
| format | Article |
| id | doaj-art-f7c87f87aaf84c8b8c6f00af8a34530f |
| institution | Kabale University |
| issn | 1994-4098 1999-8627 |
| language | Russian |
| publishDate | 2014-08-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли женской репродуктивной системы |
| spelling | doaj-art-f7c87f87aaf84c8b8c6f00af8a34530f2025-08-20T03:37:11ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-08-0102848810.17650/1994-4098-2010-0-2-84-88252Epithelioid trophoblastic tumor: Clinical presentation, diagnosis, and treatmentD. A. Lisayev0B. O. Toloknov1E. E. Makhova2I. V. Markina3N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Department of Oncology, Moscow State University of Medicine and DentistryN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Department of Oncology, Moscow State University of Medicine and DentistryN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Department of Oncology, Moscow State University of Medicine and DentistryN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Department of Oncology, Moscow State University of Medicine and DentistryEpithelioid trophoblastic tumor (ETT) is a rare form of trophoblastic disease, which is characterized by high malignancy and a number of diagnostic features: a long interval between the last pregnancy and labor and the onset of the disease; a visual pattern at gynecological examination, relatively low β-chorionic gonadotropin (CG) levels, as well as the diffuse expression of cytokeratins-7 (+++) and -18 (+++), р63 (nuclear ++), E-cadherin (+++), EGFR (+), and CD-117(++) by tumor cells, as determined by immunohistochemical assay, and focal expression of CG (++) and PLAP (+) by these cells.https://ojrs.abvpress.ru/ojrs/article/view/236epithelioid trophoblastic tumorsquamous cell carcinoma of the cervix uteriintermediate trophoblast |
| spellingShingle | D. A. Lisayev B. O. Toloknov E. E. Makhova I. V. Markina Epithelioid trophoblastic tumor: Clinical presentation, diagnosis, and treatment Опухоли женской репродуктивной системы epithelioid trophoblastic tumor squamous cell carcinoma of the cervix uteri intermediate trophoblast |
| title | Epithelioid trophoblastic tumor: Clinical presentation, diagnosis, and treatment |
| title_full | Epithelioid trophoblastic tumor: Clinical presentation, diagnosis, and treatment |
| title_fullStr | Epithelioid trophoblastic tumor: Clinical presentation, diagnosis, and treatment |
| title_full_unstemmed | Epithelioid trophoblastic tumor: Clinical presentation, diagnosis, and treatment |
| title_short | Epithelioid trophoblastic tumor: Clinical presentation, diagnosis, and treatment |
| title_sort | epithelioid trophoblastic tumor clinical presentation diagnosis and treatment |
| topic | epithelioid trophoblastic tumor squamous cell carcinoma of the cervix uteri intermediate trophoblast |
| url | https://ojrs.abvpress.ru/ojrs/article/view/236 |
| work_keys_str_mv | AT dalisayev epithelioidtrophoblastictumorclinicalpresentationdiagnosisandtreatment AT botoloknov epithelioidtrophoblastictumorclinicalpresentationdiagnosisandtreatment AT eemakhova epithelioidtrophoblastictumorclinicalpresentationdiagnosisandtreatment AT ivmarkina epithelioidtrophoblastictumorclinicalpresentationdiagnosisandtreatment |