TRAP-Induced Platelet Reactivity Is Inhibited by Omega-3 Fatty Acid-Derived Prostaglandin E3 (PGE3)

TRAP-Induced Platelet Reactivity Is Inhibited by Omega-3 Fatty Acid-Derived Prostaglandin E3 (PGE3)

<b>Background:</b> Prostaglandins are naturally occurring local mediators that can participate in the modulation of the cardiovascular system through their interaction with Gs/Gi-coupled receptors in different tissues and cells, including platelets. Thrombin is one of the most important...

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Bibliographic Details
Main Authors: José-Miguel Osete, Faustino García-Candel, Francisco-José Fernández-Gómez, Miguel Blanquer, Noemí M. Atucha, Joaquín García-Estañ, David Iyú
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomedicines
Subjects:
prostaglandin E3
thrombin
EP3 and EP4 receptors
platelet function
P-selectin
VASP phosphorylation
Online Access:https://www.mdpi.com/2227-9059/12/12/2855
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