Enhanced immune responses are accompanied by increased MAGEA expression in osteosarcoma metastases

Enhanced immune responses are accompanied by increased MAGEA expression in osteosarcoma metastases

Objective Osteosarcoma is the most common primary bone sarcoma. About 50% of patients develop metastatic disease and their 5-year survival lingers at around 20%–30%. T cell checkpoint blockade immunotherapies have revolutionised cancer treatment in the last decade, but their impact remains limited i...

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Main Authors: Hans Gelderblom, Peter A van Veelen, Noel de Miranda, Arnoud H de Ru, Judith V M G Bovée, Dina Ruano, Marieke Ijsselsteijn, Manon van der Ploeg, Siddh van Oost, Debora M Meijer, Jessica P Roelands, I H Briaire-de Bruijn, B E van den Akker, A B Kruisselbrink, P M Wijers-Koster, S W Lam, R T N Tjokrodirijo, M A J van de Sande, M L Kuijjer
Format: Article
Language:English
Published: BMJ Publishing Group 2024-08-01
Series:BMJ Oncology
Online Access:https://bmjoncology.bmj.com/content/3/1/e000472.full
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