Exocrine Pancreatic Function Tests: A Review

Exocrine pancreatic function tests (PFTs) remain of value in the diagnosis and assessment of chronic pancreatic disease. Direct intubation PFTs, using secretin/cholecystokinin or secretin/caerulein as the stimulants, continue to the the 'gold standard', although they are invasive, expensiv...

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Main Authors: Yuyuan Li, Stephen G. Chiverton, Richard H. Hunt
Format: Article
Language:English
Published: Wiley 1989-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1989/412302
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author Yuyuan Li
Stephen G. Chiverton
Richard H. Hunt
author_facet Yuyuan Li
Stephen G. Chiverton
Richard H. Hunt
author_sort Yuyuan Li
collection DOAJ
description Exocrine pancreatic function tests (PFTs) remain of value in the diagnosis and assessment of chronic pancreatic disease. Direct intubation PFTs, using secretin/cholecystokinin or secretin/caerulein as the stimulants, continue to the the 'gold standard', although they are invasive, expensive and time consuming. Tubeless indirect tests, ie, the N-benzoyl-L-tyrosyl-para-aminobe-zoic acid and pancreolauryl tests, have gained increasing acceptance particularly as screening tests. The fecal measurement of chymotrypsin remains a useful screening test for pancreatic insufficiency and fecal fat testing standard for steatorrhea. Radioisotope tests are now outdated. Estimation of pancreatic markers in serum, urine and body fluids are useful when abnormal hut miss mild disease. Combining PFTs with imaging techniques provides a rational approach to early diagnosis and gives a better assessment of the patient with chronic pancreatic disease.
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spelling doaj-art-f7a1396ebe9e406d8569caf326415a712025-02-03T01:28:39ZengWileyCanadian Journal of Gastroenterology0835-79001989-01-013415316110.1155/1989/412302Exocrine Pancreatic Function Tests: A ReviewYuyuan Li0Stephen G. Chiverton1Richard H. Hunt2Division of Gastroentrology, McMaster University Medical Centre, Hamilton, Ontario, CanadaDivision of Gastroentrology, McMaster University Medical Centre, Hamilton, Ontario, CanadaDivision of Gastroentrology, McMaster University Medical Centre, Hamilton, Ontario, CanadaExocrine pancreatic function tests (PFTs) remain of value in the diagnosis and assessment of chronic pancreatic disease. Direct intubation PFTs, using secretin/cholecystokinin or secretin/caerulein as the stimulants, continue to the the 'gold standard', although they are invasive, expensive and time consuming. Tubeless indirect tests, ie, the N-benzoyl-L-tyrosyl-para-aminobe-zoic acid and pancreolauryl tests, have gained increasing acceptance particularly as screening tests. The fecal measurement of chymotrypsin remains a useful screening test for pancreatic insufficiency and fecal fat testing standard for steatorrhea. Radioisotope tests are now outdated. Estimation of pancreatic markers in serum, urine and body fluids are useful when abnormal hut miss mild disease. Combining PFTs with imaging techniques provides a rational approach to early diagnosis and gives a better assessment of the patient with chronic pancreatic disease.http://dx.doi.org/10.1155/1989/412302
spellingShingle Yuyuan Li
Stephen G. Chiverton
Richard H. Hunt
Exocrine Pancreatic Function Tests: A Review
Canadian Journal of Gastroenterology
title Exocrine Pancreatic Function Tests: A Review
title_full Exocrine Pancreatic Function Tests: A Review
title_fullStr Exocrine Pancreatic Function Tests: A Review
title_full_unstemmed Exocrine Pancreatic Function Tests: A Review
title_short Exocrine Pancreatic Function Tests: A Review
title_sort exocrine pancreatic function tests a review
url http://dx.doi.org/10.1155/1989/412302
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