Presence of coronary artery disease in adults with newly detected diabetes mellitus
Abstract Purpose We aimed to analyze the presence and extent of coronary artery disease in patients with newly detected diabetes mellitus. Methods Clinical health examinations of asymptomatic community-dwelling adults between 2008 and 2018 at a medical center in Taiwan were reviewed. Coronary comput...
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| Language: | English |
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BMC
2025-02-01
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| Series: | BMC Cardiovascular Disorders |
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| Online Access: | https://doi.org/10.1186/s12872-024-04463-0 |
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| author | Cheng-Chien Lai Betty Chia-Chen Chang Lee-Ching Hwang |
| author_facet | Cheng-Chien Lai Betty Chia-Chen Chang Lee-Ching Hwang |
| author_sort | Cheng-Chien Lai |
| collection | DOAJ |
| description | Abstract Purpose We aimed to analyze the presence and extent of coronary artery disease in patients with newly detected diabetes mellitus. Methods Clinical health examinations of asymptomatic community-dwelling adults between 2008 and 2018 at a medical center in Taiwan were reviewed. Coronary computed tomography angiography was performed in 444 participants, of which 338, 54, and 52 were categorized as ‘without diabetes mellitus’, ‘newly detected diabetes mellitus’, and ‘known diabetes mellitus’, respectively. Results Prevalence of significant coronary artery disease (≥ 50% stenosis) was higher in participants with newly detected diabetes mellitus than in participants without diabetes mellitus (40.7% vs. 20.1%, p < 0.0001). Among those with coronary artery stenosis, the number of coronary vessels with significant obstruction (0.72 vs. 0.42, p = 0.0147) was also higher in participants with newly detected diabetes mellitus. Using multiple logistic regression analysis, new detection of diabetes mellitus was identified as an independent risk factor for significant coronary artery disease (odds ratio: 2.153, 95% confidence interval: 1.112–4.166). Conclusion Asymptomatic patients with newly detected diabetes mellitus had higher prevalence and greater extent of coronary artery disease than those without diabetes mellitus. More attention should thus be paid to the assessment of coronary artery disease in patients with newly detected diabetes mellitus. |
| format | Article |
| id | doaj-art-f769292f8b1d4a288d542241760e1e70 |
| institution | Kabale University |
| issn | 1471-2261 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj-art-f769292f8b1d4a288d542241760e1e702025-02-09T12:11:09ZengBMCBMC Cardiovascular Disorders1471-22612025-02-012511910.1186/s12872-024-04463-0Presence of coronary artery disease in adults with newly detected diabetes mellitusCheng-Chien Lai0Betty Chia-Chen Chang1Lee-Ching Hwang2Division of Nephrology, Department of Medicine, Taipei Veterans General HospitalDepartment of Family Medicine, Mackay Memorial HospitalDepartment of Family Medicine, Mackay Memorial HospitalAbstract Purpose We aimed to analyze the presence and extent of coronary artery disease in patients with newly detected diabetes mellitus. Methods Clinical health examinations of asymptomatic community-dwelling adults between 2008 and 2018 at a medical center in Taiwan were reviewed. Coronary computed tomography angiography was performed in 444 participants, of which 338, 54, and 52 were categorized as ‘without diabetes mellitus’, ‘newly detected diabetes mellitus’, and ‘known diabetes mellitus’, respectively. Results Prevalence of significant coronary artery disease (≥ 50% stenosis) was higher in participants with newly detected diabetes mellitus than in participants without diabetes mellitus (40.7% vs. 20.1%, p < 0.0001). Among those with coronary artery stenosis, the number of coronary vessels with significant obstruction (0.72 vs. 0.42, p = 0.0147) was also higher in participants with newly detected diabetes mellitus. Using multiple logistic regression analysis, new detection of diabetes mellitus was identified as an independent risk factor for significant coronary artery disease (odds ratio: 2.153, 95% confidence interval: 1.112–4.166). Conclusion Asymptomatic patients with newly detected diabetes mellitus had higher prevalence and greater extent of coronary artery disease than those without diabetes mellitus. More attention should thus be paid to the assessment of coronary artery disease in patients with newly detected diabetes mellitus.https://doi.org/10.1186/s12872-024-04463-0Coronary artery diseaseCoronary computed tomography angiographyNewly detected diabetes mellitus |
| spellingShingle | Cheng-Chien Lai Betty Chia-Chen Chang Lee-Ching Hwang Presence of coronary artery disease in adults with newly detected diabetes mellitus BMC Cardiovascular Disorders Coronary artery disease Coronary computed tomography angiography Newly detected diabetes mellitus |
| title | Presence of coronary artery disease in adults with newly detected diabetes mellitus |
| title_full | Presence of coronary artery disease in adults with newly detected diabetes mellitus |
| title_fullStr | Presence of coronary artery disease in adults with newly detected diabetes mellitus |
| title_full_unstemmed | Presence of coronary artery disease in adults with newly detected diabetes mellitus |
| title_short | Presence of coronary artery disease in adults with newly detected diabetes mellitus |
| title_sort | presence of coronary artery disease in adults with newly detected diabetes mellitus |
| topic | Coronary artery disease Coronary computed tomography angiography Newly detected diabetes mellitus |
| url | https://doi.org/10.1186/s12872-024-04463-0 |
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