Anti-K1 (Kell) Antibody Expressed in Maternal Breastmilk: A Case Report of a Neonate with Multiple Intrauterine Transfusions and Postnatal Exposure to Kell Antibody in Maternal Breastmilk
Hemolytic disease of the fetus and newborn is a common consideration in newborn medicine, especially among the jaundiced. Maternal breastmilk provides numerous benefits to the infant, including nutrition and immunologic factors. Here, we present an infant who received three intrauterine transfusions...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2017-01-01
|
| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2017/6927813 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832556258056470528 |
|---|---|
| author | Patrick DeMoss Mohamed Asfour Kelly Hersey |
| author_facet | Patrick DeMoss Mohamed Asfour Kelly Hersey |
| author_sort | Patrick DeMoss |
| collection | DOAJ |
| description | Hemolytic disease of the fetus and newborn is a common consideration in newborn medicine, especially among the jaundiced. Maternal breastmilk provides numerous benefits to the infant, including nutrition and immunologic factors. Here, we present an infant who received three intrauterine transfusions for anemia secondary to anti-K1 (Kell), anti-C, and anti-e antibodies and whose maternal breastmilk tested positive for anti-Kell antibodies. The infant required another transfusion at 4 weeks of life for anemia. We review the pathophysiology of anti-Kell antibodies, the immunology of breast milk, and the intersection of these two topics. |
| format | Article |
| id | doaj-art-f73e2c674a064753822af7781e9b06a1 |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-f73e2c674a064753822af7781e9b06a12025-02-03T05:45:57ZengWileyCase Reports in Pediatrics2090-68032090-68112017-01-01201710.1155/2017/69278136927813Anti-K1 (Kell) Antibody Expressed in Maternal Breastmilk: A Case Report of a Neonate with Multiple Intrauterine Transfusions and Postnatal Exposure to Kell Antibody in Maternal BreastmilkPatrick DeMoss0Mohamed Asfour1Kelly Hersey2Blair E. Batson Children’s Hospital, Department of Pediatrics, Jackson, MS, USADepartment of Pathology, University of Mississippi Medical Center, Jackson, MS, USABlair E. Batson Children’s Hospital, Department of Neonatology, Jackson, MS, USAHemolytic disease of the fetus and newborn is a common consideration in newborn medicine, especially among the jaundiced. Maternal breastmilk provides numerous benefits to the infant, including nutrition and immunologic factors. Here, we present an infant who received three intrauterine transfusions for anemia secondary to anti-K1 (Kell), anti-C, and anti-e antibodies and whose maternal breastmilk tested positive for anti-Kell antibodies. The infant required another transfusion at 4 weeks of life for anemia. We review the pathophysiology of anti-Kell antibodies, the immunology of breast milk, and the intersection of these two topics.http://dx.doi.org/10.1155/2017/6927813 |
| spellingShingle | Patrick DeMoss Mohamed Asfour Kelly Hersey Anti-K1 (Kell) Antibody Expressed in Maternal Breastmilk: A Case Report of a Neonate with Multiple Intrauterine Transfusions and Postnatal Exposure to Kell Antibody in Maternal Breastmilk Case Reports in Pediatrics |
| title | Anti-K1 (Kell) Antibody Expressed in Maternal Breastmilk: A Case Report of a Neonate with Multiple Intrauterine Transfusions and Postnatal Exposure to Kell Antibody in Maternal Breastmilk |
| title_full | Anti-K1 (Kell) Antibody Expressed in Maternal Breastmilk: A Case Report of a Neonate with Multiple Intrauterine Transfusions and Postnatal Exposure to Kell Antibody in Maternal Breastmilk |
| title_fullStr | Anti-K1 (Kell) Antibody Expressed in Maternal Breastmilk: A Case Report of a Neonate with Multiple Intrauterine Transfusions and Postnatal Exposure to Kell Antibody in Maternal Breastmilk |
| title_full_unstemmed | Anti-K1 (Kell) Antibody Expressed in Maternal Breastmilk: A Case Report of a Neonate with Multiple Intrauterine Transfusions and Postnatal Exposure to Kell Antibody in Maternal Breastmilk |
| title_short | Anti-K1 (Kell) Antibody Expressed in Maternal Breastmilk: A Case Report of a Neonate with Multiple Intrauterine Transfusions and Postnatal Exposure to Kell Antibody in Maternal Breastmilk |
| title_sort | anti k1 kell antibody expressed in maternal breastmilk a case report of a neonate with multiple intrauterine transfusions and postnatal exposure to kell antibody in maternal breastmilk |
| url | http://dx.doi.org/10.1155/2017/6927813 |
| work_keys_str_mv | AT patrickdemoss antik1kellantibodyexpressedinmaternalbreastmilkacasereportofaneonatewithmultipleintrauterinetransfusionsandpostnatalexposuretokellantibodyinmaternalbreastmilk AT mohamedasfour antik1kellantibodyexpressedinmaternalbreastmilkacasereportofaneonatewithmultipleintrauterinetransfusionsandpostnatalexposuretokellantibodyinmaternalbreastmilk AT kellyhersey antik1kellantibodyexpressedinmaternalbreastmilkacasereportofaneonatewithmultipleintrauterinetransfusionsandpostnatalexposuretokellantibodyinmaternalbreastmilk |