Synthesis of 11-(Piperazin-1-yl)-5H-dibenzo[b,e] [1,4]diazepine on Kilo Scale

Synthesis of 11-(Piperazin-1-yl)-5H-dibenzo[b,e] [1,4]diazepine on Kilo Scale

A synthesis of 11-(piperazin-1yl)-5 H-dibenzo[b,e][1,4]diazepine on kilo scale without any chromatographic purification step is reported. Key steps involved are Ullmann condensation, catalytic hydrogenation, and catalyzed cyclization.

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Bibliographic Details
Main Authors:	Rahul S. Kalhapure, Bhushan P. Patil, Mahantesh N. Jadhav, Laxmikant A. Kawle, Sanjay B. Wagh
Format:	Article
Language:	English
Published:	Wiley 2011-01-01
Series:	E-Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2011/212014
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