Evaluation of TaMFT-3A and TaMKK3-4A alleles on wheat pre-harvest sprouting

Pre‐harvest sprouting (PHS) is a significant challenge affecting global production of wheat (Triticum aestivum L.). Resistance to PHS is governed by both genetic and environmental factors, making reliable molecular markers essential for enhancing PHS resistance through molecular marker‐assisted sele...

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Main Authors: Bo-Wen Zhang, Bai-Song Yang, Xiao-Neng Wan, Xin Ma, Kai-Di Lyu, Han Wang, Shu-Ying Yang, Hui-Hui Zhang, Shu-Nv Hao, Jian Ma, Guo-Zhong Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Plant Science
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Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2025.1594385/full
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author Bo-Wen Zhang
Bo-Wen Zhang
Bai-Song Yang
Xiao-Neng Wan
Xin Ma
Kai-Di Lyu
Han Wang
Shu-Ying Yang
Hui-Hui Zhang
Shu-Nv Hao
Jian Ma
Guo-Zhong Sun
author_facet Bo-Wen Zhang
Bo-Wen Zhang
Bai-Song Yang
Xiao-Neng Wan
Xin Ma
Kai-Di Lyu
Han Wang
Shu-Ying Yang
Hui-Hui Zhang
Shu-Nv Hao
Jian Ma
Guo-Zhong Sun
author_sort Bo-Wen Zhang
collection DOAJ
description Pre‐harvest sprouting (PHS) is a significant challenge affecting global production of wheat (Triticum aestivum L.). Resistance to PHS is governed by both genetic and environmental factors, making reliable molecular markers essential for enhancing PHS resistance through molecular marker‐assisted selection (MAS). Genes TaMFT-3A and TaMKK3-4A have been cloned in wheat and are known to regulate PHS resistance in white-grained varieties. In this study, we assessed the allelic variations in these genes and their combined effects on PHS resistance using two recombinant inbred line (RIL) populations, Wanxianbaimaizi/Zhongyou 9507 (WZ) and Wanxianbaimaizi/Jing 411 (WJ), under two distinct field environmental conditions. PHS resistance was assessed by measuring seed germination in physiologically mature stage, correlation and ANOVA were used to analyze PHS data. The germination percentage (GP) and germination index (GI) were significantly correlated across both RIL populations. Specific allelic variations at positions -222, +646, and +666 in the TaMFT-3A gene strongly correlated with PHS resistance. The CGA haplotype at these loci was linked to the highest resistance, while the TAA haplotype was associated with the lowest resistance levels. Additionally, haplotype variation at the +660 locus of TaMKK3-4A demonstrated a weak but environmentally modulated correlation with PHS resistance. This study provides a theoretical foundation for utilizing TaMFT-3A and TaMKK3-4A in molecular breeding strategies to enhance wheat resilience to PHS.
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spelling doaj-art-f7301d8edf124de683335331c745d6ff2025-08-20T02:31:09ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2025-05-011610.3389/fpls.2025.15943851594385Evaluation of TaMFT-3A and TaMKK3-4A alleles on wheat pre-harvest sproutingBo-Wen Zhang0Bo-Wen Zhang1Bai-Song Yang2Xiao-Neng Wan3Xin Ma4Kai-Di Lyu5Han Wang6Shu-Ying Yang7Hui-Hui Zhang8Shu-Nv Hao9Jian Ma10Guo-Zhong Sun11College of Agronomy, Jilin Agricultural University, Changchun, ChinaNational Engineering Research Center for Crop Molecular Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaNational Engineering Research Center for Crop Molecular Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaNational Engineering Research Center for Crop Molecular Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaNational Engineering Research Center for Crop Molecular Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaNational Engineering Research Center for Crop Molecular Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaNational Engineering Research Center for Crop Molecular Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaNational Engineering Research Center for Crop Molecular Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaNational Engineering Research Center for Crop Molecular Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaNational Engineering Research Center for Crop Molecular Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaCollege of Agronomy, Jilin Agricultural University, Changchun, ChinaNational Engineering Research Center for Crop Molecular Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaPre‐harvest sprouting (PHS) is a significant challenge affecting global production of wheat (Triticum aestivum L.). Resistance to PHS is governed by both genetic and environmental factors, making reliable molecular markers essential for enhancing PHS resistance through molecular marker‐assisted selection (MAS). Genes TaMFT-3A and TaMKK3-4A have been cloned in wheat and are known to regulate PHS resistance in white-grained varieties. In this study, we assessed the allelic variations in these genes and their combined effects on PHS resistance using two recombinant inbred line (RIL) populations, Wanxianbaimaizi/Zhongyou 9507 (WZ) and Wanxianbaimaizi/Jing 411 (WJ), under two distinct field environmental conditions. PHS resistance was assessed by measuring seed germination in physiologically mature stage, correlation and ANOVA were used to analyze PHS data. The germination percentage (GP) and germination index (GI) were significantly correlated across both RIL populations. Specific allelic variations at positions -222, +646, and +666 in the TaMFT-3A gene strongly correlated with PHS resistance. The CGA haplotype at these loci was linked to the highest resistance, while the TAA haplotype was associated with the lowest resistance levels. Additionally, haplotype variation at the +660 locus of TaMKK3-4A demonstrated a weak but environmentally modulated correlation with PHS resistance. This study provides a theoretical foundation for utilizing TaMFT-3A and TaMKK3-4A in molecular breeding strategies to enhance wheat resilience to PHS.https://www.frontiersin.org/articles/10.3389/fpls.2025.1594385/fullwheatpre-harvest spoutingrecombinant inbred linehaplotypemarker-assisted selection
spellingShingle Bo-Wen Zhang
Bo-Wen Zhang
Bai-Song Yang
Xiao-Neng Wan
Xin Ma
Kai-Di Lyu
Han Wang
Shu-Ying Yang
Hui-Hui Zhang
Shu-Nv Hao
Jian Ma
Guo-Zhong Sun
Evaluation of TaMFT-3A and TaMKK3-4A alleles on wheat pre-harvest sprouting
Frontiers in Plant Science
wheat
pre-harvest spouting
recombinant inbred line
haplotype
marker-assisted selection
title Evaluation of TaMFT-3A and TaMKK3-4A alleles on wheat pre-harvest sprouting
title_full Evaluation of TaMFT-3A and TaMKK3-4A alleles on wheat pre-harvest sprouting
title_fullStr Evaluation of TaMFT-3A and TaMKK3-4A alleles on wheat pre-harvest sprouting
title_full_unstemmed Evaluation of TaMFT-3A and TaMKK3-4A alleles on wheat pre-harvest sprouting
title_short Evaluation of TaMFT-3A and TaMKK3-4A alleles on wheat pre-harvest sprouting
title_sort evaluation of tamft 3a and tamkk3 4a alleles on wheat pre harvest sprouting
topic wheat
pre-harvest spouting
recombinant inbred line
haplotype
marker-assisted selection
url https://www.frontiersin.org/articles/10.3389/fpls.2025.1594385/full
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