Biomechanics of Disc Degeneration

Disc degeneration and associated disorders are among the most debated topics in the orthopedic literature over the past few decades. These may be attributed to interrelated mechanical, biochemical, and environmental factors. The treatment options vary from conservative approaches to surgery, dependi...

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Main Authors: V. Palepu, M. Kodigudla, V. K. Goel
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Advances in Orthopedics
Online Access:http://dx.doi.org/10.1155/2012/726210
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author V. Palepu
M. Kodigudla
V. K. Goel
author_facet V. Palepu
M. Kodigudla
V. K. Goel
author_sort V. Palepu
collection DOAJ
description Disc degeneration and associated disorders are among the most debated topics in the orthopedic literature over the past few decades. These may be attributed to interrelated mechanical, biochemical, and environmental factors. The treatment options vary from conservative approaches to surgery, depending on the severity of degeneration and response to conservative therapies. Spinal fusion is considered to be the “gold standard” in surgical methods till date. However, the association of adjacent level degeneration has led to the evolution of motion preservation technologies like spinal arthroplasty and posterior dynamic stabilization systems. These new technologies are aimed to address pain and preserve motion while maintaining a proper load sharing among various spinal elements. This paper provides an elaborative biomechanical review of the technologies aimed to address the disc degeneration and reiterates the point that biomechanical efficacy followed by long-term clinical success will allow these nonfusion technologies as alternatives to fusion, at least in certain patient population.
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spelling doaj-art-f711180977704682be300bf8dd0f77122025-02-03T06:07:59ZengWileyAdvances in Orthopedics2090-34642090-34722012-01-01201210.1155/2012/726210726210Biomechanics of Disc DegenerationV. Palepu0M. Kodigudla1V. K. Goel2Departments of Bioengineering and Orthopaedic Surgery, Engineering Center for Orthopaedic Research Excellence (E-CORE), Colleges of Engineering and Medicine, University of Toledo, Toledo, 5046 NI, OH 43606, USADepartments of Bioengineering and Orthopaedic Surgery, Engineering Center for Orthopaedic Research Excellence (E-CORE), Colleges of Engineering and Medicine, University of Toledo, Toledo, 5046 NI, OH 43606, USADepartments of Bioengineering and Orthopaedic Surgery, Engineering Center for Orthopaedic Research Excellence (E-CORE), Colleges of Engineering and Medicine, University of Toledo, Toledo, 5046 NI, OH 43606, USADisc degeneration and associated disorders are among the most debated topics in the orthopedic literature over the past few decades. These may be attributed to interrelated mechanical, biochemical, and environmental factors. The treatment options vary from conservative approaches to surgery, depending on the severity of degeneration and response to conservative therapies. Spinal fusion is considered to be the “gold standard” in surgical methods till date. However, the association of adjacent level degeneration has led to the evolution of motion preservation technologies like spinal arthroplasty and posterior dynamic stabilization systems. These new technologies are aimed to address pain and preserve motion while maintaining a proper load sharing among various spinal elements. This paper provides an elaborative biomechanical review of the technologies aimed to address the disc degeneration and reiterates the point that biomechanical efficacy followed by long-term clinical success will allow these nonfusion technologies as alternatives to fusion, at least in certain patient population.http://dx.doi.org/10.1155/2012/726210
spellingShingle V. Palepu
M. Kodigudla
V. K. Goel
Biomechanics of Disc Degeneration
Advances in Orthopedics
title Biomechanics of Disc Degeneration
title_full Biomechanics of Disc Degeneration
title_fullStr Biomechanics of Disc Degeneration
title_full_unstemmed Biomechanics of Disc Degeneration
title_short Biomechanics of Disc Degeneration
title_sort biomechanics of disc degeneration
url http://dx.doi.org/10.1155/2012/726210
work_keys_str_mv AT vpalepu biomechanicsofdiscdegeneration
AT mkodigudla biomechanicsofdiscdegeneration
AT vkgoel biomechanicsofdiscdegeneration