Gastrointestinal microbiome and gluten in celiac disease
Coeliac disease (CD), also known as gluten sensitive enteropathy, is an autoimmune intestinal disease induced by gluten in genetically susceptible individuals. Gluten is a common ingredient in daily diet and is one of the main environmental factors to induce coeliac disease. Adhering to gluten free...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-01-01
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| Series: | Annals of Medicine |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/07853890.2021.1990392 |
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| author | Xingxing Wu Lin Qian Kexin Liu Jing Wu Zhaowei Shan |
| author_facet | Xingxing Wu Lin Qian Kexin Liu Jing Wu Zhaowei Shan |
| author_sort | Xingxing Wu |
| collection | DOAJ |
| description | Coeliac disease (CD), also known as gluten sensitive enteropathy, is an autoimmune intestinal disease induced by gluten in genetically susceptible individuals. Gluten is a common ingredient in daily diet and is one of the main environmental factors to induce coeliac disease. Adhering to gluten free diet (GFD) is an effective method for treating CD. Microbiota plays an extremely important role in maintaining human health, and diet is the main factor to regulate the composition and function of gut microbiota. Recent studies have shown that gluten metabolism is closely related to gastrointestinal tract (GIT) microbiota. With the increasing prevalence of coeliac disease, there is a need for alternative treatments to GFD. In this review, biological medication of gluten, relationship between gluten and gut microflora, effect of GFD on GIT microflora, and effect of probiotics on CD were reviewed. By analysing the research progress on relationship between gluten and gastrointestinal microbiome in coeliac disease, this review tried to explore the prospective and potential mechanism of microecological agents in treating coeliac disease. |
| format | Article |
| id | doaj-art-f70b6c4be0cb4106bee3ebde510d2333 |
| institution | Kabale University |
| issn | 0785-3890 1365-2060 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Medicine |
| spelling | doaj-art-f70b6c4be0cb4106bee3ebde510d23332025-08-20T03:44:04ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602021-01-015311797180510.1080/07853890.2021.1990392Gastrointestinal microbiome and gluten in celiac diseaseXingxing Wu0Lin Qian1Kexin Liu2Jing Wu3Zhaowei Shan4Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, ChinaAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, ChinaAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, ChinaInstitute of Chinese Medicine, Nanjing Drum Tower Hospital, Nanjing University, Drum Tower Clinical Medicine College of Nanjing University of Chinese Medicine, Nanjing, ChinaAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, ChinaCoeliac disease (CD), also known as gluten sensitive enteropathy, is an autoimmune intestinal disease induced by gluten in genetically susceptible individuals. Gluten is a common ingredient in daily diet and is one of the main environmental factors to induce coeliac disease. Adhering to gluten free diet (GFD) is an effective method for treating CD. Microbiota plays an extremely important role in maintaining human health, and diet is the main factor to regulate the composition and function of gut microbiota. Recent studies have shown that gluten metabolism is closely related to gastrointestinal tract (GIT) microbiota. With the increasing prevalence of coeliac disease, there is a need for alternative treatments to GFD. In this review, biological medication of gluten, relationship between gluten and gut microflora, effect of GFD on GIT microflora, and effect of probiotics on CD were reviewed. By analysing the research progress on relationship between gluten and gastrointestinal microbiome in coeliac disease, this review tried to explore the prospective and potential mechanism of microecological agents in treating coeliac disease.https://www.tandfonline.com/doi/10.1080/07853890.2021.1990392Glutengastrointestinal microbiomecoeliac diseasegluten free dietprobiotics |
| spellingShingle | Xingxing Wu Lin Qian Kexin Liu Jing Wu Zhaowei Shan Gastrointestinal microbiome and gluten in celiac disease Annals of Medicine Gluten gastrointestinal microbiome coeliac disease gluten free diet probiotics |
| title | Gastrointestinal microbiome and gluten in celiac disease |
| title_full | Gastrointestinal microbiome and gluten in celiac disease |
| title_fullStr | Gastrointestinal microbiome and gluten in celiac disease |
| title_full_unstemmed | Gastrointestinal microbiome and gluten in celiac disease |
| title_short | Gastrointestinal microbiome and gluten in celiac disease |
| title_sort | gastrointestinal microbiome and gluten in celiac disease |
| topic | Gluten gastrointestinal microbiome coeliac disease gluten free diet probiotics |
| url | https://www.tandfonline.com/doi/10.1080/07853890.2021.1990392 |
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