State-of-the-Art Treatments for Sarcoidosis

Sarcoidosis is a heterogeneous disease with various treatment indications. Although it affects mainly the lungs, sarcoidosis can affect every organ, especially when the disease course is chronic and protracted. Regular patient follow-up is recommended for early recognition of active, ongoing organ-s...

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Main Authors: Ilias C. Papanikolaou, Emmanouil Antonakis, Aggeliki Pandi
Format: Article
Language:English
Published: Houston Methodist DeBakey Heart & Vascular Center 2022-03-01
Series:Methodist DeBakey Cardiovascular Journal
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Online Access:https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1068
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author Ilias C. Papanikolaou
Emmanouil Antonakis
Aggeliki Pandi
author_facet Ilias C. Papanikolaou
Emmanouil Antonakis
Aggeliki Pandi
author_sort Ilias C. Papanikolaou
collection DOAJ
description Sarcoidosis is a heterogeneous disease with various treatment indications. Although it affects mainly the lungs, sarcoidosis can affect every organ, especially when the disease course is chronic and protracted. Regular patient follow-up is recommended for early recognition of active, ongoing organ-specific granulomatous inflammation to avoid progression to irreversible fibrosis. In this review, we elaborate on treatment indications and various anti-sarcoidosis regimens proven useful in clinical trials. We also review specialized treatment of specific disease manifestations, with a focus on cardiac sarcoidosis. We also report on treatment for special conditions such as fatigue and small fiber neuropathy. Treatment for sarcoidosis is an emerging landscape, with new data complementing the existing knowledge.
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publishDate 2022-03-01
publisher Houston Methodist DeBakey Heart & Vascular Center
record_format Article
series Methodist DeBakey Cardiovascular Journal
spelling doaj-art-f6eda89008eb4db387eb797c71c8fef02025-08-20T02:22:19ZengHouston Methodist DeBakey Heart & Vascular CenterMethodist DeBakey Cardiovascular Journal1947-61082022-03-011829410510.14797/mdcvj.1068468State-of-the-Art Treatments for SarcoidosisIlias C. Papanikolaou0https://orcid.org/0000-0003-1391-2925Emmanouil Antonakis1Aggeliki Pandi2Corfu General Hospital, CorfuCorfu General Hospital, CorfuCorfu General Hospital, CorfuSarcoidosis is a heterogeneous disease with various treatment indications. Although it affects mainly the lungs, sarcoidosis can affect every organ, especially when the disease course is chronic and protracted. Regular patient follow-up is recommended for early recognition of active, ongoing organ-specific granulomatous inflammation to avoid progression to irreversible fibrosis. In this review, we elaborate on treatment indications and various anti-sarcoidosis regimens proven useful in clinical trials. We also review specialized treatment of specific disease manifestations, with a focus on cardiac sarcoidosis. We also report on treatment for special conditions such as fatigue and small fiber neuropathy. Treatment for sarcoidosis is an emerging landscape, with new data complementing the existing knowledge.https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1068sarcoidosis treatmentcardiac sarcoidosisadvanced sarcoidosisneurosarcoidosis
spellingShingle Ilias C. Papanikolaou
Emmanouil Antonakis
Aggeliki Pandi
State-of-the-Art Treatments for Sarcoidosis
Methodist DeBakey Cardiovascular Journal
sarcoidosis treatment
cardiac sarcoidosis
advanced sarcoidosis
neurosarcoidosis
title State-of-the-Art Treatments for Sarcoidosis
title_full State-of-the-Art Treatments for Sarcoidosis
title_fullStr State-of-the-Art Treatments for Sarcoidosis
title_full_unstemmed State-of-the-Art Treatments for Sarcoidosis
title_short State-of-the-Art Treatments for Sarcoidosis
title_sort state of the art treatments for sarcoidosis
topic sarcoidosis treatment
cardiac sarcoidosis
advanced sarcoidosis
neurosarcoidosis
url https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1068
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AT emmanouilantonakis stateofthearttreatmentsforsarcoidosis
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